Protein Alignment CG3397 and Akr1b7

DIOPT Version :10

• Sequence 1: NP_650140.1
• Gene: CG3397 / 41454
• FlyBaseID: FBgn0037975
• Length: 342
• Species: Drosophila melanogaster
• Sequence 2: NP_033861.2
• Gene: Akr1b7 / 11997
• MGIID: 101918
• Length: 316
• Species: Mus musculus
• Alignment Length: 297
• Identity: 62/297 - (20%)
• Similarity: 118/297 - (39%)
• Gaps: 70/297 - (23%)

  Fly    61 VQEAIRSGINYIDTAPFYGQGKSEELLGQALKD------VPREAYYIATKV-ARYELDPNNMFDY 118
            |:.||.:|..:||.|..|   .:|..:|:|:::      |.||..:|.:|: |.:         :
Mouse    32 VKAAIDAGYRHIDCAYVY---HNENEVGEAIQEKIKENAVKREDLFIVSKLWATF---------F 84

  Fly   119 TAAKARESVKRSLELLQLDRVDVLQVHDVDAAPSLDMVLNETIP-------------------VL 164
            ..:..:::.:.:|..|:||.:|:..||    .|......|..:|                   .:
Mouse    85 EKSLVKKAFQNTLSDLKLDYLDLYLVH----WPQGFQAGNALLPKDNKGKVLLSKSTFLDAWEAM 145

  Fly   165 EEYVQAGKARFIGVTAYDVDVLKECAERGKGRIQVVLNY--ARYTLLDNTLLRHMKAFQE----- 222
            ||.|..|..:.:|::.::           ..:|:.:||.  .::..:.|.:..|....||
Mouse   146 EELVDQGLVKALGISNFN-----------HFQIERLLNKPGLKHKPVTNQIESHPYLTQEKLIQY 199

  Fly   223 -MGVGVVCAAAHSLGLLSNAGPQSWHPGSPELLAVGKRGAEICQKRNVELGKLAMYYTMQLDGAA 286
             ...|:...|...||  |...|.: .|..|.::.:.|. .||..|....:.::.:.:.:|.:...
Mouse   200 CQSKGIAVTAYSPLG--SPDRPYA-KPEDPVVMEIPKI-KEIAAKHKKTVAQVLIRFHVQRNVVV 260

  Fly   287 TFLIGIPNRKLLRINLDAIFDGLTSHEQ--EVLQYLR 321
            ......|:|  ::.||. :||...|.|.  .:|.:.|
Mouse   261 IPKSVTPSR--IQENLQ-VFDFQLSEEDMAAILSFNR 294

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3397	NP_650140.1	AKR_galDH	22..315	CDD:381389	60/289 (21%)
Akr1b7	NP_033861.2	AKR_AKR1B1-19	10..316	CDD:381333	62/297 (21%)