Protein Alignment CG12224 and YPL088W

DIOPT Version :10

• Sequence 1: NP_650139.4
• Gene: CG12224 / 41453
• FlyBaseID: FBgn0037974
• Length: 339
• Species: Drosophila melanogaster
• Sequence 2: NP_015237.1
• Gene: YPL088W / 856017
• SGDID: S000006009
• Length: 342
• Species: Saccharomyces cerevisiae
• Alignment Length: 348
• Identity: 78/348 - (22%)
• Similarity: 146/348 - (41%)
• Gaps: 75/348 - (21%)

  Fly    26 QLGSTGLHVSKLAIGGSPLCNLFFDDY---DREEGILMVQEAIRSGINYIDTAPFY--GQSEVLL 85
            :||::||.:|.:.||.....:..:.|:   |:.:...:::.....|:...|||.||  |.||.::
Yeast     8 RLGNSGLKISPIVIGCMSYGSKKWADWVIEDKTQIFKIMKHCYDKGLRTFDTADFYSNGLSERII 72

  Fly    86 GQALK--DVPREAYYIATKVARY-------------------GLDPKNMFDYSADKARESVKRSL 129
            .:.|:  .:.||...|.||:  |                   .||..|....|.......|:.|:
Yeast    73 KEFLEYYSIKRETVVIMTKI--YFPVDETLDLHHNFTLNEFEELDLSNQRGLSRKHIIAGVENSV 135

  Fly   130 ERLQLDRVDILQVHDVDAAPNLDIVLNETIPVLEEYVQAGKARFIGVT---AYDVDVLKECAERG 191
            :||. ..:|:||:|.:|.    :..:.|.:..|.:.|:||..|:||.:   |.:...|:..|::
Yeast   136 KRLG-TYIDLLQIHRLDH----ETPMKEIMKALNDVVEAGHVRYIGASSMLATEFAELQFTADK- 194

  Fly   192 KGRIQVVLNYARYTLLDNTLLRYMKDFQKMGVGVVCAAAHSLGLL---RNAGPHASHPGSQ---- 249
            .|..|.:.:.:.|.||      |.:|.:::   :..|..|::|||   .||....:.|.:|
Yeast   195 YGWFQFISSQSYYNLL------YREDEREL---IPFAKRHNIGLLPWSPNARGMLTRPLNQSTDR 250

  Fly   250 -----------------EILAVAKRGAEICQQRNVELGKLAMYYTMQLDGAATFLIGIPNRKLLR 297
                             |...:..|..::.:.:.|.:..|::.:.  |......::|:.....:.
Yeast   251 IKSDPTFKSLHLDNLEEEQKEIINRVEKVSKDKKVSMAMLSIAWV--LHKGCHPIVGLNTTARVD 313

  Fly   298 INLDAIFDGLTSHEQEVLQYLRE 320
            ..:.|:...||   :|.::||.|
Yeast   314 EAIAALQVTLT---EEEIKYLEE 333

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12224	NP_650139.4	AKR_galDH	22..313	CDD:381389	74/339 (22%)
YPL088W	NP_015237.1	AKR_EcYajO-like	5..332	CDD:381305	76/345 (22%)