Protein Alignment CG12224 and AAD14

DIOPT Version :9

• Sequence 1: NP_650139.3
• Gene: CG12224 / 41453
• FlyBaseID: FBgn0037974
• Length: 338
• Species: Drosophila melanogaster
• Sequence 2: NP_014068.1
• Gene: AAD14 / 855385
• SGDID: S000005275
• Length: 376
• Species: Saccharomyces cerevisiae
• Alignment Length: 383
• Identity: 91/383 - (23%)
• Similarity: 147/383 - (38%)
• Gaps: 110/383 - (28%)

  Fly    25 RQLGST-GLHVSKLAIGGSPLCNL---FFDDYDREEGILMVQEAIRSGINYIDTAPFL----SEV 81
            |.|..| |:.||.|.:||:.:.:.   |....::|:...::.....:|.|.||||...    ||:
Yeast    19 RVLSKTAGIRVSPLILGGASIGDAWSGFMGSMNKEQAFELLDAFYEAGGNCIDTANSYQNEESEI 83

  Fly    82 LLGQALKDVP-REAYYIATKVA----RYGLDPKNMFDYSADKARE---SVKRSLERLQLDRVDIL 138
            .:|:.:.... |:...||||..    :|.:......:|..:..|.   ||:.||.:||.|.:|||
Yeast    84 WIGEWMASRKLRDQIVIATKFTGDYKKYEVGGGKSANYCGNHKRSLHVSVRDSLRKLQTDWIDIL 148

  Fly   139 QVHDVDAAPNLDIVLNETIPVLEEYVQAGKARFIGV--------------------TAYDV---- 179
            .:|..|...:::.|::.    |...||.||..::||                    |.:.|
Yeast   149 YIHWWDYMSSIEEVMDS----LHILVQQGKVLYLGVSDTPAWVVSAANYYATSHGKTPFSVYQGK 209

  Fly   180 -DVLKECAER-------------------GKGRIQVVLNYARYTLLDNTLLRYMKDFQKMGVGVV 224
             :||....||                   |.||.|              ..:.|::.:|.|.|
Yeast   210 WNVLNRDFERDIIPMARHFGMALAPWDVMGGGRFQ--------------SKKAMEERKKNGEG-- 258

  Fly   225 CAAAHSLGLLRN--AGPHASHPGSQEI-LAVAKRGAEICQQRNVE-LGKLAMYYTMQLDGAATFL 285
                     ||.  .||..:     |: :.:::...:|.::...| :..:|:.|..........|
Yeast   259 ---------LRTFVGGPEQT-----ELEVKISEALTKIAEEHGTESVTAIAIAYVRSKAKNVFPL 309

  Fly   286 IGIPNRKL--LRINLDAIFDGLTSHEQEVLQYLRENV-----FTKSYSWGSTLSTAKL 336
            ||  .||:  |:.|::|:...||   .|.::||...|     |.||........|.||
Yeast   310 IG--GRKIEHLKQNIEALSIKLT---PEQIEYLESIVPFDVGFPKSLIGDDPAVTKKL 362

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12224	NP_650139.3	AKR_galDH	22..311	CDD:381389	81/351 (23%)
AAD14	NP_014068.1	AKR_AKR9A3_9B1-4	20..338	CDD:381373	82/356 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0.985475	Normalized mean entropy	S2698
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.860