Protein Alignment CG12224 and Akr1c21

DIOPT Version :10

• Sequence 1: NP_650139.4
• Gene: CG12224 / 41453
• FlyBaseID: FBgn0037974
• Length: 339
• Species: Drosophila melanogaster
• Sequence 2: NP_084177.2
• Gene: Akr1c21 / 77337
• MGIID: 1924587
• Length: 323
• Species: Mus musculus
• Alignment Length: 293
• Identity: 71/293 - (24%)
• Similarity: 121/293 - (41%)
• Gaps: 64/293 - (21%)

  Fly    64 AIRSGINYIDTAPFYGQSEVLLGQALKD------VPREAYYIATKVARYGLDPKNMFDYSADKAR 122
            ||.:|.::.|:|..| .:|..:|:|::.      |.||..:..:||....|.|        :..|
Mouse    41 AIDAGFHHFDSASVY-NTEDHVGEAIRSKIADGTVRREDIFYTSKVWCTSLHP--------ELVR 96

  Fly   123 ESVKRSLERLQLDRVDILQVH------------DVDAAPNL---DIVLNETIPVLEEYVQAGKAR 172
            .|::|||::||.|.||:..:|            .||....|   .:.|..|...:|:...||..:
Mouse    97 ASLERSLQKLQFDYVDLYLIHYPMALKPGEENFPVDEHGKLIFDRVDLCATWEAMEKCKDAGLTK 161

  Fly   173 FIGVTAYDVDVLKECAERGKGRIQVVLNY--ARYTLLDNTL-----LRYMK--DFQKMGVGVVCA 228
            .|||:.::.           .:::::||.  .:|..:.|.:     |..||  ||.| ...:|..
Mouse   162 SIGVSNFNY-----------RQLEMILNKPGLKYKPVCNQVECHPYLNQMKLLDFCK-SKDIVLV 214

  Fly   229 AAHSLGLLRNAGPHASHPGSQEILAVAKRGAEICQQRNVELGKLAMYYTMQLDGAATFLIGIPNR 293
            |...||..|..|  .....|..:|.....|: :.::.|.....:|:.|.:|..      |.:.|.
Mouse   215 AYGVLGTQRYGG--WVDQNSPVLLDEPVLGS-MAKKYNRTPALIALRYQLQRG------IVVLNT 270

  Fly   294 KL----LRINLDAIFDGLTSHEQEVLQYLRENV 322
            .|    ::.|:......|:|.:.:||..|..|:
Mouse   271 SLKEERIKENMQVFEFQLSSEDMKVLDGLNRNM 303

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12224	NP_650139.4	AKR_galDH	22..313	CDD:381389	67/282 (24%)
Akr1c21	NP_084177.2	AKR_AKR1C1-35	6..308	CDD:381334	71/293 (24%)