Protein Alignment CG12224 and kcnab1b

DIOPT Version :10

• Sequence 1: NP_650139.4
• Gene: CG12224 / 41453
• FlyBaseID: FBgn0037974
• Length: 339
• Species: Drosophila melanogaster
• Sequence 2: XP_683674.2
• Gene: kcnab1b / 555922
• ZFINID: ZDB-GENE-070912-690
• Length: 399
• Species: Danio rerio
• Alignment Length: 334
• Identity: 85/334 - (25%)
• Similarity: 148/334 - (44%)
• Gaps: 61/334 - (18%)

  Fly    18 KVRRMEYRQLGSTGLHVSKLAIG-----GSPLCNLFFDDYDREEGILMVQEAIRSGINYIDTAPF 77
            |:..|:||.||.:||.||.|.:|     |..:.:      :..|.::.:  |..:|:|..|||..
Zfish    65 KLTGMKYRNLGKSGLRVSCLGLGTWVTFGGQISD------EVAEQLMTI--AYENGVNLFDTAEV 121

  Fly    78 Y--GQSEVLLGQALKDV--PREAYYIATKV-------ARYGLDPKNMFDYSADKARESVKRSLER 131
            |  |::|::||..:|..  .|.:..|.||:       ...||..|::.        |.:|.||:|
Zfish   122 YSAGKAEIILGNIIKKKCWRRSSLVITTKLYWGGKAETERGLSRKHII--------EGLKGSLQR 178

  Fly   132 LQLDRVDILQVHDVDAAPNLDIVLNETIPVLEEYVQAGKARFIGVTAYDVDVLKEC--AERGKGR 194
            ||||.||::..:    .|:.:..:.|.:..:...:..|.:.:.|.:.:....:.|.  ..|....
Zfish   179 LQLDYVDVVFAN----RPDSNTPMEEIVRAMTHVINHGMSMYWGTSRWSAMEIMEAYSVARQFNL 239

  Fly   195 IQVVLNYARYTLL--DNTLLRYMKDFQKMGVGVVCAAAHSLGLL----RNAGPHASHPG------ 247
            |..|...|.|.|.  |...::..:.:.|:|||||..:..:.|::    .|..|.:|...
Zfish   240 IPPVCEQAEYHLFQRDKVEMQLPELYHKIGVGVVSWSPLACGIITGKYENGIPESSRASMKSYQW 304

  Fly   248 -SQEIL--------AVAKRGAEICQQRNVELGKLAMYYTMQLDGAATFLIGIPNRKLLRINLDAI 303
             .::||        |..|....|.::.:..|.:||:.:.::.:|.::.|:|..|...|..||.||
Zfish   305 LKEKILGEDGRKQQAKLKELTHIAERLSCTLPQLAIAWCLRNEGVSSVLLGTSNPAQLTENLGAI 369

  Fly   304 --FDGLTSH 310
              ...:|:|
Zfish   370 QVLPKITAH 378

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12224	NP_650139.4	AKR_galDH	22..313	CDD:381389	84/330 (25%)
kcnab1b	XP_683674.2	AKR_SF	69..391	CDD:444925	84/330 (25%)