Protein Alignment CG12224 and Hk

DIOPT Version :10

• Sequence 1: NP_650139.4
• Gene: CG12224 / 41453
• FlyBaseID: FBgn0037974
• Length: 339
• Species: Drosophila melanogaster
• Sequence 2: NP_001259401.1
• Gene: Hk / 31955
• FlyBaseID: FBgn0263220
• Length: 887
• Species: Drosophila melanogaster
• Alignment Length: 247
• Identity: 67/247 - (27%)
• Similarity: 115/247 - (46%)
• Gaps: 36/247 - (14%)

  Fly     3 GSLPATFVKGFHDEEKVRRMEYRQLGSTGLHVSKLAIGGSPLCNLFFDDYDREEGILMVQEAIRS 67
            ||.||..::  |.......:.|:.||.:||.:|.:.:|..|:.:....| |:.|.||.:  ||.|
  Fly   186 GSNPALPLR--HGSTPTPGLRYKNLGKSGLRISNVGLGTWPVFSPGVSD-DQAEAILKL--AIES 245

  Fly    68 GINYIDTAPFYGQSEVLLGQALKDV--PREAYYIATKV------ARYGLDPKNMFDYSADKARES 124
            |||..|.:..:.::|:  |:.|:..  .|.||.|.|||      ...||..|::.        |.
  Fly   246 GINLFDISEAHSETEI--GKILQRAGWKRTAYVITTKVYWSTKSEERGLSRKHII--------EC 300

  Fly   125 VKRSLERLQLDRVDILQVHDVDAAPNLDIVLNETIPVLEEYVQAGKARFIGVTAY-DVDVLK--- 185
            |:.||:||||..:||:.:|..|....:::|     ..:...:|.|.|.:.|...: .|::::
  Fly   301 VRASLQRLQLQYIDIVIIHKADPMCPMEVV-----RAMSYVIQQGWAMYWGTARWSQVEIMEAYT 360

  Fly   186 ECAERGKGRIQVVLNYARYTLL--DNTLLRYMKDFQKMGVGVVCAAAHSLGL 235
            .|  |....|..::..:.|.:.  :...|...:.:.|:|||::.....|:.|
  Fly   361 NC--RQFNCITPIVEQSEYHMFCREKCELYLPEMYNKIGVGLMAWGPLSMAL 410

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12224	NP_650139.4	AKR_galDH	22..313	CDD:381389	62/228 (27%)
Hk	NP_001259401.1	AKR_AKR6B1	203..535	CDD:381368	62/228 (27%)