Protein Alignment CG12224 and Akr1c19

DIOPT Version :10

• Sequence 1: NP_650139.4
• Gene: CG12224 / 41453
• FlyBaseID: FBgn0037974
• Length: 339
• Species: Drosophila melanogaster
• Sequence 2: NP_001094046.1
• Gene: Akr1c19 / 307096
• RGDID: 1562954
• Length: 323
• Species: Rattus norvegicus
• Alignment Length: 304
• Identity: 75/304 - (24%)
• Similarity: 122/304 - (40%)
• Gaps: 47/304 - (15%)

  Fly    47 LFFDDYDREE-----GILMVQEAIRSGINYIDTAPFYGQSEVLLGQALKD------VPREAYYIA 100
            |.|..|..||     .:..:..|:.:|..:||||..| |:|..:|||:|.      |.||..:|.
  Rat    19 LGFGTYKPEEVPENKPLEAIHLAVEAGFRHIDTAYVY-QTENHVGQAIKSKIAAGIVKREDIFIT 82

  Fly   101 TKVARYGLDPKNMFDYSADKARESVKRSLERLQLDRVDILQVH--------------DVDAAPNL 151
            ||:......|:.:.        .|:::||:.||||.||:..:|              |.:.....
  Rat    83 TKLWCTFHRPEMVL--------SSLEKSLKNLQLDYVDLYIIHYPMQMKSGEDMFPEDENGKTLF 139

  Fly   152 DIV-LNETIPVLEEYVQAGKARFIGVTAYDVDVLKECAERGKGRIQVVLNYARYTLLDN--TLLR 213
            |.| |..|...:|:...||.|:.|||:.::...|::...:...:.:.|.|.....|..|  .||.
  Rat   140 DTVDLCATWEAMEKCKDAGLAKSIGVSNFNRRQLEKILNKPGLKYKPVCNQVECHLYLNQSKLLN 204

  Fly   214 YMKDFQKMGVGVVCAAAHSLGLLRNAGPHASHPGSQEILAVAKRGAEICQQRNVELGKLAMYYTM 278
            |.|...     :|..|..:||..|   |......|..:|.......::.::......::|:.|
  Rat   205 YCKSRD-----IVLVAYCALGSQR---PKRWVDPSSPVLLNDPVLCDVAKKHQRSSAQIALRY-- 259

  Fly   279 QLDGAATFLIGIPNRKLLRINLDAIFDGLTSHEQEVLQYLRENV 322
            ||......|........::.|:......|.|.:.::|..|..|:
  Rat   260 QLQRGNVVLAQSYKENEIKENIQVFEFELPSEDMKILDSLDRNL 303

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12224	NP_650139.4	AKR_galDH	22..313	CDD:381389	72/293 (25%)
Akr1c19	NP_001094046.1	AKR_AKR1C1-35	6..308	CDD:381334	75/304 (25%)