Protein Alignment CG12224 and AKR7L

DIOPT Version :9

• Sequence 1: NP_650139.3
• Gene: CG12224 / 41453
• FlyBaseID: FBgn0037974
• Length: 338
• Species: Drosophila melanogaster
• Sequence 2: NP_001335350.1
• Gene: AKR7L / 246181
• HGNCID: 24056
• Length: 331
• Species: Homo sapiens
• Alignment Length: 293
• Identity: 69/293 - (23%)
• Similarity: 109/293 - (37%)
• Gaps: 76/293 - (25%)

  Fly    65 IRSGINYIDTAPFL-----SEVLLG-----QALKDVPREAYYIATKVARY---GLDPKNMFDYSA 116
            :..|...|||| ||     ||.:||     ....|.   ...||||...:   .|.|
Human    36 LERGHTEIDTA-FLYSDGQSETILGGLGLRMGSSDC---RVKIATKANPWIGNSLKP-------- 88

  Fly   117 DKARESVKRSLERLQLDRVDILQVHDVDAAPNLDIVLNETIPVLEEYVQAGKARFIGVTAYDV-D 180
            |..|..::.||:|||..|||:..:|    ||:....:.||:....:..|.||...:|::.|.. :
Human    89 DSVRSQLETSLKRLQCPRVDLFYLH----APDHSAPVEETLRACHQLHQEGKFVELGLSNYAAWE 149

  Fly   181 VLKECAE-RGKGRIQVVLNYARYTL----LDNTLLRYMKDFQKMGVGVVCAAAHSL--GLLRNAG 238
            |.:.|.. :..|.|...:....|:.    ::..|...::.|     |:...|.:.|  |||....
Human   150 VAEICTLCKSNGWILPTVYQGMYSATTRQVETELFPCLRHF-----GLRFYAYNPLAGGLLTGKY 209

  Fly   239 PHASHPGSQEI------------------------LAVAKR------GAEICQQRNVELGKLAMY 273
            .:....|.|.:                        :|:.::      ||......:..|  ..||
Human   210 KYEDKDGKQPVGRFFGTQWAEIYRNHFWKEHHFEGIALVEKALQAAYGASAPSMTSAAL--RWMY 272

  Fly   274 YTMQLDGA--ATFLIGIPNRKLLRINLDAIFDG 304
            :..||.||  ...::|:.:.:.|..||.|..:|
Human   273 HHSQLQGAHGDAVILGMSSLEQLEQNLAAAEEG 305

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12224	NP_650139.3	AKR_galDH	22..311	CDD:381389	69/293 (24%)
AKR7L	NP_001335350.1	Aldo_ket_red	10..318	CDD:119408	69/293 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D396894at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.920