Protein Alignment CG12224 and Akr7a2

DIOPT Version :9

• Sequence 1: NP_650139.3
• Gene: CG12224 / 41453
• FlyBaseID: FBgn0037974
• Length: 338
• Species: Drosophila melanogaster
• Sequence 2: NP_599234.1
• Gene: Akr7a2 / 171445
• RGDID: 620311
• Length: 338
• Species: Rattus norvegicus
• Alignment Length: 310
• Identity: 69/310 - (22%)
• Similarity: 111/310 - (35%)
• Gaps: 86/310 - (27%)

  Fly    53 DREEGILMVQEAIRSGINYIDTAPFL-----SEVLLGQ----------ALKDVPREAYYIATKVA 102
            |.......|:..:..|:|.:||| |:     ||.:||.          .:|        ||||..
  Rat    31 DASASAATVRAFLERGLNELDTA-FMYCDGQSESILGSLGLGLGSGDCTVK--------IATKAN 86

  Fly   103 RYGLDPKNMFDYSADKARESVKRSLERLQLDRVDILQVHDVDAAPNLDIVLNETIPVLEEYVQAG 167
            .:  |.|::   ..|..|..::.||:|||..|||:..:|    ||:....:.||:...::..|.|
  Rat    87 PW--DGKSL---KPDSVRSQLETSLKRLQCPRVDLFYLH----APDHGTPIVETLQACQQLHQEG 142

  Fly   168 KARFIGVTAYD----VDVLKECAERG-------KGRIQVVLNYARYTLLDNTLLRYMKDFQKMGV 221
            |...:|::.|.    .::...|...|       :|............||  ..|||.
  Rat   143 KFVELGLSNYASWEVAEIYTLCKSNGWILPTVYQGMYNATTRQVETELL--PCLRYF-------- 197

  Fly   222 GVVCAAAHSL--GLLRNAGPHASHPGSQ------------------------EILAVAKRGAEIC 260
            |:...|.:.|  |||.....:....|.|                        |.:|:.::..:..
  Rat   198 GLRFYAYNPLAGGLLTGKYRYEDKDGKQPEGRFFGNSWSETYRNRFWKEHHFEAIALVEKALKTT 262

  Fly   261 QQRNVELGKLA----MYYTMQLDGAA--TFLIGIPNRKLLRINLDAIFDG 304
            ...:......|    ||:..||.|..  ..::|:.:.:.|..||.|..:|
  Rat   263 YGTSAPSMTSAALRWMYHHSQLQGTRGDAVILGMSSLEQLEQNLAATEEG 312

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12224	NP_650139.3	AKR_galDH	22..311	CDD:381389	69/310 (22%)
Akr7a2	NP_599234.1	Tas	21..334	CDD:223739	69/310 (22%)
		Aldo_ket_red	21..325	CDD:119408	69/310 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D396894at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920