Protein Alignment CG12224 and Kcnab2

DIOPT Version :9

• Sequence 1: NP_650139.3
• Gene: CG12224 / 41453
• FlyBaseID: FBgn0037974
• Length: 338
• Species: Drosophila melanogaster
• Sequence 2: XP_011248499.1
• Gene: Kcnab2 / 16498
• MGIID: 109239
• Length: 414
• Species: Mus musculus
• Alignment Length: 368
• Identity: 90/368 - (24%)
• Similarity: 154/368 - (41%)
• Gaps: 90/368 - (24%)

  Fly    22 MEYRQLGSTGLHVSKLAIG-----GSPLCNLFFDDYDREEGILMVQEAIRSGINYIDTAPFL--- 78
            |:||.||.:||.||.|.:|     |..:.:      :..|.::.:  |..:|||..|||...
Mouse    68 MKYRNLGKSGLRVSCLGLGTWVTFGGQITD------EMAEHLMTL--AYDNGINLFDTAEVYAAG 124

  Fly    79 -SEVLLGQALKDV--PREAYYIATKV-------ARYGLDPKNMFDYSADKARESVKRSLERLQLD 133
             :||:||..:|..  .|.:..|.||:       ...||..|::.        |.:|.|||||||:
Mouse   125 KAEVVLGNIIKKKGWRRSSLVITTKIFWGGKAETERGLSRKHII--------EGLKASLERLQLE 181

  Fly   134 RVDILQVHDVDAAPNLDI--------------VLNETIPVLEEYVQAGKARFIGVTAYDVDVLKE 184
            .||::..:..|  ||..:              ::.||:..:...:..|.|.:.|.:.:....:.|
Mouse   182 YVDVVFANRPD--PNTPMEAGDPFSSFKSRTFIIEETVRAMTHVINQGMAMYWGTSRWSSMEIME 244

  Fly   185 C--AERGKGRIQVVLNYARYTLL--DNTLLRYMKDFQKMGVGVVCAAAHSLGLLR---NAG--PH 240
            .  ..|....|..:...|.|.:.  :...::..:.|.|:|||.:..:..:.|::.   ::|  |:
Mouse   245 AYSVARQFNLIPPICEQAEYHMFQREKVEVQLPELFHKIGVGAMTWSPLACGIVSGKYDSGIPPY 309

  Fly   241 --ASHPGSQ----EIL--------AVAKRGAEICQQRNVELGKLAMYYTMQLDGAATFLIGIPNR 291
              ||..|.|    :||        |..|....|.::....|.:||:.:.::.:|.::.|:|..|.
Mouse   310 SRASLKGYQWLKDKILSEEGRRQQAKLKELQAIAERLGCTLPQLAIAWCLRNEGVSSVLLGASNA 374

  Fly   292 KLLRINLDAIFDGLTSHEQEVLQYLRENVF--------TKSYS 326
            :.|..|:.||         :||..|..::.        .|.||
Mouse   375 EQLMENIGAI---------QVLPKLSSSIVHEIDSILGNKPYS 408

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12224	NP_650139.3	AKR_galDH	22..311	CDD:381389	84/343 (24%)
Kcnab2	XP_011248499.1	Aldo_ket_red_shaker	69..394	CDD:381367	86/351 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	72	1.000	Inparanoid score	I5281
Isobase	1	0.950	-	0.985475	Normalized mean entropy	S2698
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.910