Protein Alignment CG12224 and Akr1b7

DIOPT Version :10

• Sequence 1: NP_650139.4
• Gene: CG12224 / 41453
• FlyBaseID: FBgn0037974
• Length: 339
• Species: Drosophila melanogaster
• Sequence 2: NP_033861.2
• Gene: Akr1b7 / 11997
• MGIID: 101918
• Length: 316
• Species: Mus musculus
• Alignment Length: 243
• Identity: 53/243 - (21%)
• Similarity: 100/243 - (41%)
• Gaps: 52/243 - (21%)

  Fly    61 VQEAIRSGINYIDTA-PFYGQSEVLLGQALKD------VPREAYYIATKV-ARYGLDPKNMFDYS 117
            |:.||.:|..:||.| .::.::||  |:|:::      |.||..:|.:|: |.:         :.
Mouse    32 VKAAIDAGYRHIDCAYVYHNENEV--GEAIQEKIKENAVKREDLFIVSKLWATF---------FE 85

  Fly   118 ADKARESVKRSLERLQLDRVDILQVH---DVDAAPNL-------DIVLNETI-----PVLEEYVQ 167
            ....:::.:.:|..|:||.:|:..||   ...|...|       .::|:::.     ..:||.|.
Mouse    86 KSLVKKAFQNTLSDLKLDYLDLYLVHWPQGFQAGNALLPKDNKGKVLLSKSTFLDAWEAMEELVD 150

  Fly   168 AGKARFIGVTAYDVDVLKECAERGKGRIQVVLNY--ARYTLLDNTLLRYMKDFQKMGVGVVCAAA 230
            .|..:.:|::.::...::....:...:.:.|.|.  :...|....|::|.   |..|:.|  .|.
Mouse   151 QGLVKALGISNFNHFQIERLLNKPGLKHKPVTNQIESHPYLTQEKLIQYC---QSKGIAV--TAY 210

  Fly   231 HSLGLLRNAGPHASHPGSQEILAV----AKRGAEICQ-------QRNV 267
            ..||...........|...||..:    ||....:.|       ||||
Mouse   211 SPLGSPDRPYAKPEDPVVMEIPKIKEIAAKHKKTVAQVLIRFHVQRNV 258

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12224	NP_650139.4	AKR_galDH	22..313	CDD:381389	53/243 (22%)
Akr1b7	NP_033861.2	AKR_AKR1B1-19	10..316	CDD:381333	53/243 (22%)