Protein Alignment CG18547 and AKR1C3

DIOPT Version :9

• Sequence 1: NP_650138.1
• Gene: CG18547 / 41452
• FlyBaseID: FBgn0037973
• Length: 345
• Species: Drosophila melanogaster
• Sequence 2: NP_001240837.1
• Gene: AKR1C3 / 8644
• HGNCID: 386
• Length: 323
• Species: Homo sapiens
• Alignment Length: 303
• Identity: 75/303 - (24%)
• Similarity: 123/303 - (40%)
• Gaps: 81/303 - (26%)

  Fly    62 AVKSGINYIDTAPWYGQGRSEEVLGLALK------DVPRESYYIATKV----ARYELDYDKMFDF 116
            |:::|..:||:|..|   .:||.:|||::      .|.||..:..:|:    .|.||
Human    41 AIEAGFRHIDSAHLY---NNEEQVGLAIRSKIADGSVKREDIFYTSKLWSTFHRPEL-------- 94

  Fly   117 SAKKTRESVEKSLKLLGLDYVDVIQIH---DIEFAKDL-----------DIV-INETLPTLEQLV 166
                .|.::|.|||...|||||:..||   .::..::|           ||| :..|...:|:..
Human    95 ----VRPALENSLKKAQLDYVDLYLIHSPMSLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCK 155

  Fly   167 KEGKARFIGVSAYPISVLKEFLTRTAGRLDTVLTYAR-YTLTDETLLEYLDFFKSQNLGVICAAA 230
            ..|.|:.||||.:....|:..|.:...:...|..... :...:.:.|  |||.||::  ::..|.
Human   156 DAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNRSKL--LDFCKSKD--IVLVAY 216

  Fly   231 HALGLLTNAGPQPW----HPASDEQK---AIARK--------ASEVCKERGVELGKLAMYYTMSG 280
            .|||   :...:.|    .|...|..   |:|:|        |.....:|||.:  ||..|
Human   217 SALG---SQRDKRWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVV--LAKSY---- 272

  Fly   281 LPEVSTFLTGMQTRQLLRINLDANEVGLSDKEQEVLRYLKENV 323
                        ..|.:|.|:...|..|:.::.:.:..|..|:
Human   273 ------------NEQRIRQNVQVFEFQLTAEDMKAIDGLDRNL 303

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG18547	NP_650138.1	Tas	22..331	CDD:223739	75/303 (25%)
		Aldo_ket_red	24..321	CDD:294321	74/299 (25%)
AKR1C3	NP_001240837.1	ARA1	9..305	CDD:223729	75/303 (25%)
		Tas	17..297	CDD:223739	73/295 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165158420
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.840