Protein Alignment CG18547 and KCNAB2

DIOPT Version :10

• Sequence 1: NP_650138.1
• Gene: CG18547 / 41452
• FlyBaseID: FBgn0037973
• Length: 345
• Species: Drosophila melanogaster
• Sequence 2: NP_001186791.1
• Gene: KCNAB2 / 8514
• HGNCID: 6229
• Length: 415
• Species: Homo sapiens
• Alignment Length: 359
• Identity: 89/359 - (24%)
• Similarity: 154/359 - (42%)
• Gaps: 72/359 - (20%)

  Fly    22 MEYRNLGKTGLQVSKVSFG-----GGALCANYGFDLEEGIKTVHEAVKSGINYIDTAPWYGQGRS 81
            |:||||||:||:||.:..|     ||.:..    ::.|.:.|:  |..:|||..|||..|..|::
Human    70 MKYRNLGKSGLRVSCLGLGTWVTFGGQITD----EMAEQLMTL--AYDNGINLFDTAEVYAAGKA 128

  Fly    82 EEVLG--LALKDVPRESYYIATKV---ARYELDYDKMFDFSAKKTRESVEKSLKLLGLDYVDVI- 140
            |.|||  :..|...|.|..|.||:   .:.|.:.    ..|.|...|.::.||:.|.|:||||:
Human   129 EVVLGNIIKKKGWRRSSLVITTKIFWGGKAETER----GLSRKHIIEGLKASLERLQLEYVDVVF 189

  Fly   141 ----------QIHDIEFAKDLDIVINETLPTLEQLVKEGKARFIGVS---------AYPISVLKE 186
                      :......:|....:|.||:..:..::.:|.|.:.|.|         ||  ||.::
Human   190 ANRPDPNTPMEGDPFSSSKSRTFIIEETVRAMTHVINQGMAMYWGTSRWSSMEIMEAY--SVARQ 252

  Fly   187 F-LTRTAGRLDTVLTYARYTL--TDETLLEYLDFFKSQNLGVICAAAHALGLLT---NAGPQPWH 245
            | ||      ..:...|.|.:  .::..::..:.|....:|.:..:..|.|:::   ::|..|:.
Human   253 FNLT------PPICEQAEYHMFQREKVEVQLPELFHKIGVGAMTWSPLACGIVSGKYDSGIPPYS 311

  Fly   246 PAS----------------DEQKAIARKASEVCKERGVELGKLAMYYTMSGLPEVSTFLTGMQTR 294
            .||                ..|:|..::...:.:..|..|.:||:.:.:.. ..||:.|.|....
Human   312 RASLKGYQWLKDKILSEEGRRQQAKLKELQAIAERLGCTLPQLAIAWCLRN-EGVSSVLLGASNA 375

  Fly   295 QLLRINLDANEVGLSDKEQEVLRYLKENVLTKPF 328
            ..|..|:.|.:| |......::..:...:..||:
Human   376 DQLMENIGAIQV-LPKLSSSIIHEIDSILGNKPY 408

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG18547	NP_650138.1	AKR_galDH	22..314	CDD:381389	87/343 (25%)
KCNAB2	NP_001186791.1	Aldo_ket_red_shaker	71..395	CDD:381367	86/343 (25%)