Protein Alignment CG18547 and KCNAB2

DIOPT Version :9

• Sequence 1: NP_650138.1
• Gene: CG18547 / 41452
• FlyBaseID: FBgn0037973
• Length: 345
• Species: Drosophila melanogaster
• Sequence 2: XP_016858110.1
• Gene: KCNAB2 / 8514
• HGNCID: 6229
• Length: 435
• Species: Homo sapiens
• Alignment Length: 359
• Identity: 89/359 - (24%)
• Similarity: 154/359 - (42%)
• Gaps: 72/359 - (20%)

  Fly    22 MEYRNLGKTGLQVSKVSFG-----GGALCANYGFDLEEGIKTVHEAVKSGINYIDTAPWYGQGRS 81
            |:||||||:||:||.:..|     ||.:..    ::.|.:.|:  |..:|||..|||..|..|::
Human    90 MKYRNLGKSGLRVSCLGLGTWVTFGGQITD----EMAEQLMTL--AYDNGINLFDTAEVYAAGKA 148

  Fly    82 EEVLG--LALKDVPRESYYIATKV---ARYELDYDKMFDFSAKKTRESVEKSLKLLGLDYVDVI- 140
            |.|||  :..|...|.|..|.||:   .:.|.:.    ..|.|...|.::.||:.|.|:||||:
Human   149 EVVLGNIIKKKGWRRSSLVITTKIFWGGKAETER----GLSRKHIIEGLKASLERLQLEYVDVVF 209

  Fly   141 ----------QIHDIEFAKDLDIVINETLPTLEQLVKEGKARFIGVS---------AYPISVLKE 186
                      :......:|....:|.||:..:..::.:|.|.:.|.|         ||  ||.::
Human   210 ANRPDPNTPMEGDPFSSSKSRTFIIEETVRAMTHVINQGMAMYWGTSRWSSMEIMEAY--SVARQ 272

  Fly   187 F-LTRTAGRLDTVLTYARYTL--TDETLLEYLDFFKSQNLGVICAAAHALGLLT---NAGPQPWH 245
            | ||      ..:...|.|.:  .::..::..:.|....:|.:..:..|.|:::   ::|..|:.
Human   273 FNLT------PPICEQAEYHMFQREKVEVQLPELFHKIGVGAMTWSPLACGIVSGKYDSGIPPYS 331

  Fly   246 PAS----------------DEQKAIARKASEVCKERGVELGKLAMYYTMSGLPEVSTFLTGMQTR 294
            .||                ..|:|..::...:.:..|..|.:||:.:.:.. ..||:.|.|....
Human   332 RASLKGYQWLKDKILSEEGRRQQAKLKELQAIAERLGCTLPQLAIAWCLRN-EGVSSVLLGASNA 395

  Fly   295 QLLRINLDANEVGLSDKEQEVLRYLKENVLTKPF 328
            ..|..|:.|.:| |......::..:...:..||:
Human   396 DQLMENIGAIQV-LPKLSSSIIHEIDSILGNKPY 428

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG18547	NP_650138.1	Tas	22..331	CDD:223739	89/359 (25%)
		Aldo_ket_red	24..321	CDD:294321	86/348 (25%)
KCNAB2	XP_016858110.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0667
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	69	1.000	Inparanoid score	I5328
Isobase	1	0.950	-	0.985475	Normalized mean entropy	S2698
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R634
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.840