Protein Alignment CG18547 and Akr1c6

DIOPT Version :10

• Sequence 1: NP_650138.1
• Gene: CG18547 / 41452
• FlyBaseID: FBgn0037973
• Length: 345
• Species: Drosophila melanogaster
• Sequence 2: NP_085114.1
• Gene: Akr1c6 / 83702
• MGIID: 1933427
• Length: 323
• Species: Mus musculus
• Alignment Length: 298
• Identity: 74/298 - (24%)
• Similarity: 126/298 - (42%)
• Gaps: 71/298 - (23%)

  Fly    62 AVKSGINYIDTAPWYGQGRSEEVLGLALKD------VPRESYYIATKV----ARYELDYDKMFDF 116
            |:.:|..:||:|..|   ::|:.:|||::.      |.||..:..:||    .|.||
Mouse    41 AIDAGFRHIDSASMY---QNEKEVGLAIRSKIADGTVKREDIFYTSKVWCTFHRPEL-------- 94

  Fly   117 SAKKTRESVEKSLKLLGLDYVDVIQIH--------DIEFAKD------LDIV-INETLPTLEQLV 166
                .|..:|:|||.|.|||||:..||        :....||      .|.| |.:|...:|:..
Mouse    95 ----VRVCLEQSLKQLQLDYVDLYLIHFPMAMKPGENYLPKDENGKLIYDAVDICDTWEAMEKCK 155

  Fly   167 KEGKARFIGVSAYPISVLKEFLTRTAGRLDTVLTYAR-YTLTDETLLEYLDFFKSQNLGVICAAA 230
            ..|.|:.||||.:....|::.|.:...:...|..... :...::..|  |||.:|::  ::..|.
Mouse   156 DAGLAKSIGVSNFNRRQLEKILKKPGLKYKPVCNQVECHPYLNQGKL--LDFCRSKD--IVLVAY 216

  Fly   231 HALGLLTNAGPQPWHPASDEQKAIARKASEVCKERGVELGKLAMYYTMSGLPEVSTFLTGMQ--- 292
            .|||             |..:|....::|.|..:..| ||.:|..|..:  |.:......:|
Mouse   217 SALG-------------SHREKQWVDQSSPVLLDNPV-LGSMAKKYNRT--PALIALRYQLQRGV 265

  Fly   293 -------TRQLLRINLDANEVGLSDKEQEVLRYLKENV 323
                   :.:.::.|:...|..|:.::.:||..|.:|:
Mouse   266 VVLAKSFSEKRIKENMQVFEFQLTSEDMKVLDDLNKNI 303

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG18547	NP_650138.1	AKR_galDH	22..314	CDD:381389	70/287 (24%)
Akr1c6	NP_085114.1	AKR_AKR1C1-35	6..308	CDD:381334	74/298 (25%)