Protein Alignment CG18547 and Akr1c12

DIOPT Version :10

• Sequence 1: NP_650138.1
• Gene: CG18547 / 41452
• FlyBaseID: FBgn0037973
• Length: 345
• Species: Drosophila melanogaster
• Sequence 2: NP_038805.2
• Gene: Akr1c12 / 622402
• MGIID: 1351661
• Length: 323
• Species: Mus musculus
• Alignment Length: 333
• Identity: 81/333 - (24%)
• Similarity: 129/333 - (38%)
• Gaps: 69/333 - (20%)

  Fly    37 VSFGGGALCANYGFDL--------EEGIKTVHEAVKSGINYIDTAPWYGQGRSEEVLGLALKD-- 91
            |....|.|....||..        .:.::....|:..|..::|||..|   :.||.:|.|::.
Mouse     8 VKLNDGHLIPALGFGTYKPKEVPKSKSLEAACLALDVGYRHVDTAYAY---QVEEEIGQAIQSKI 69

  Fly    92 ----VPRESYYIATKV----ARYELDYDKMFDFSAKKTRESVEKSLKLLGLDYVDVIQIH----- 143
                |.||..:|.||:    .|.||            .:.::|||||.|.|||||:..||
Mouse    70 KAGVVKREDLFITTKLWCGCFRPEL------------VKPALEKSLKSLQLDYVDLYLIHYPVPM 122

  Fly   144 ---DIEFAKD------LDIV-INETLPTLEQLVKEGKARFIGVSAYPISVLKEFLTRTAGRLDTV 198
               |.|...|      ||.| ..:|...||:....|..:.||||.:....|:..|.:...:...|
Mouse   123 KPGDNESPLDENGKFLLDTVDFCDTWERLEECKDAGLVKSIGVSNFNHRQLERILNKPGLKYKPV 187

  Fly   199 LTYAR-YTLTDETLLEYLDFFKSQNLGVICAAAHALGLLTNAGPQPWHPASDEQKAIARKASEVC 262
            ..... :...:::.|  ||:.||:::.::     |.|.|   |.|.:....|:...:......:|
Mouse   188 CNQVECHLYLNQSKL--LDYCKSKDIVLV-----AYGAL---GTQRYKEWVDQNSPVLLNDPVLC 242

  Fly   263 -----KERGVELGKLAMYYTMSGLPEVSTFLTGMQTRQLLRINLDANEVGLSDKEQEVLRYLKEN 322
                 .:|...|..|...:....:|...:|     ....:|.||...|..||.::.:.|..|.:|
Mouse   243 DVAKRNKRSPALIALRYLFQRGIVPLAQSF-----KENEMRENLQVFEFQLSPEDMKTLDGLNKN 302

  Fly   323 VLTKPFDW 330
            ....|.::
Mouse   303 FRYLPAEF 310

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG18547	NP_650138.1	AKR_galDH	22..314	CDD:381389	77/315 (24%)
Akr1c12	NP_038805.2	AKR_AKR1C1-35	6..308	CDD:381334	80/329 (24%)