Protein Alignment CG18547 and AKR1B15

DIOPT Version :9

• Sequence 1: NP_650138.1
• Gene: CG18547 / 41452
• FlyBaseID: FBgn0037973
• Length: 345
• Species: Drosophila melanogaster
• Sequence 2: NP_001074007.2
• Gene: AKR1B15 / 441282
• HGNCID: 37281
• Length: 344
• Species: Homo sapiens
• Alignment Length: 349
• Identity: 87/349 - (24%)
• Similarity: 134/349 - (38%)
• Gaps: 82/349 - (23%)

  Fly    30 TGLQVS--KVSFGGGALCANYGFDLEEGIKTVHEAVKSGIN----YIDTAPWYGQGRSEEVLGLA 88
            |||:.|  |.:...|.|...|...|   :..|.||||..|:    :||.|.:|   .::..:|.|
Human    28 TGLKSSLLKDTTSAGPLLRPYPASL---LGKVKEAVKVAIDAEYRHIDCAYFY---ENQHEVGEA 86

  Fly    89 L------KDVPRESYYIATKVARYELDYDKMFDFSAKKTRESVEKSLKLLGLDYVDVIQIH---- 143
            :      |.|.||..:|.:||      :...|:  ....|::.||:||.|.|.|:||..||
Human    87 IQEKIQEKAVMREDLFIVSKV------WPTFFE--RPLVRKAFEKTLKDLKLSYLDVYLIHWPQG 143

  Fly   144 ----DIEFAKD------------LDIVINETLPTLEQLVKEGKARFIGVSAYPISVLKEFLTRTA 192
                |..|.||            ||     ....:|:||.||..:.:|||.:....::..|.:..
Human   144 FKTGDDFFPKDDKGNMISGKGTFLD-----AWEAMEELVDEGLVKALGVSNFNHFQIERLLNKPG 203

  Fly   193 GRLDTVLTYARYT--------LTDETLLEYLDFFKSQNLGVICAAAHALGLLTNAGPQPWHPASD 249
                  |.|...|        ||.|.|::|     ..:.|:...|...||    :..:||....|
Human   204 ------LKYKPVTNQVECHPYLTQEKLIQY-----CHSKGITVTAYSPLG----SPDRPWAKPED 253

  Fly   250 EQKAIARKASEV-CKERGVELGKLAMYYTMSGLPEVSTFLTGMQTRQLLRINLDANEVGLSDKEQ 313
            .......|..|: .|.:......|..::....:..:...:|.....:    |:...:..|||:|.
Human   254 PSLLEDPKIKEIAAKHKKTTAQVLIRFHIQRNVTVIPKSMTPAHIVE----NIQVFDFKLSDEEM 314

  Fly   314 EVLRYLKENVLTKPFDW-EGNELE 336
            ..:.....|  .:.||: |.:.||
Human   315 ATILSFNRN--WRAFDFKEFSHLE 336

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG18547	NP_650138.1	Tas	22..331	CDD:223739	84/342 (25%)
		Aldo_ket_red	24..321	CDD:294321	81/331 (24%)
AKR1B15	NP_001074007.2	ARA1	56..325	CDD:223729	73/305 (24%)
		Tas	57..317	CDD:223739	71/294 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165158431
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.930