Protein Alignment CG18547 and akr7a3

DIOPT Version :10

• Sequence 1: NP_650138.1
• Gene: CG18547 / 41452
• FlyBaseID: FBgn0037973
• Length: 345
• Species: Drosophila melanogaster
• Sequence 2: NP_001002369.1
• Gene: akr7a3 / 436642
• ZFINID: ZDB-GENE-040718-62
• Length: 323
• Species: Danio rerio
• Alignment Length: 338
• Identity: 87/338 - (25%)
• Similarity: 130/338 - (38%)
• Gaps: 82/338 - (24%)

  Fly    37 VSFGGGALCANYGFDLEEGIKTVHEAVKSGINYIDTAPWYGQGRSEEVLG-LALKDVPRESYYIA 100
            ::|||.|       |.....:.|...::.|.:.:|||..|..|::|.::| :.|.:..|    ||
Zfish    14 MAFGGRA-------DAHMSSQLVRVFLERGHSELDTALMYNDGQAESIIGDMQLPETVR----IA 67

  Fly   101 TKVARYE---LDYDKMFDFSAKKTRESVEKSLKLLGLDYVDVIQIHDIEFAKDLDIVINETLPTL 162
            ||...:|   |..|.:        |:.:|.|||.|....|.:..:|    |.|....|.:||...
Zfish    68 TKANPWEGKTLKPDSV--------RKQLESSLKRLRRQTVQIFYLH----APDHQNPIQDTLQAC 120

  Fly   163 EQLVKEGKARFIGVSAY---PISVLKEFLTRTAGRLDTVL--TYARYTLTDET-LLEYLDFFKSQ 221
            .||.||||...:|:|.|   .::.:..........|.||.  .|...|...|| ||..|.:|
Zfish   121 NQLHKEGKFEELGLSNYASWEVAEIYSICKHNNWVLPTVYQGMYNATTRQVETELLPCLRYF--- 182

  Fly   222 NLGVICAAAHAL--GLLTNA-------GPQP--------WHPASDE--------------QKAIA 255
              |:...|.:.|  ||||..       |.||        |..|..:              |||:
Zfish   183 --GIRFFAYNPLAGGLLTGKYHYEDKDGAQPAGRFFGNNWANAYRDRYWKESHFQGIDGVQKAL- 244

  Fly   256 RKASEVCKERGVELGKLAMYYTMSGL--PEVSTFLTGMQTRQLLRINLDANEVGLSDKEQEVLRY 318
             :::...::..:....:...|..|.|  .:....:.||.:.:.|..||.|...|  ..:|||:..
Zfish   245 -ESAYGSEKPSLTSAAIRWMYHHSHLKGDQGDGVIIGMSSMEQLNENLTAAAEG--PLKQEVVDA 306

  Fly   319 LKENVLTKPFDWE 331
            .|.       .||
Zfish   307 FKH-------AWE 312

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG18547	NP_650138.1	AKR_galDH	22..314	CDD:381389	81/319 (25%)
akr7a3	NP_001002369.1	AKR_AKR7A1-5	7..311	CDD:381301	85/335 (25%)