Protein Alignment CG18547 and Akr1c19

DIOPT Version :10

• Sequence 1: NP_650138.1
• Gene: CG18547 / 41452
• FlyBaseID: FBgn0037973
• Length: 345
• Species: Drosophila melanogaster
• Sequence 2: NP_001013807.2
• Gene: Akr1c19 / 432720
• MGIID: 2653678
• Length: 323
• Species: Mus musculus
• Alignment Length: 314
• Identity: 78/314 - (24%)
• Similarity: 126/314 - (40%)
• Gaps: 83/314 - (26%)

  Fly    56 IKTVHEAVKSGINYIDTAPWYGQGRSEEVLGLALKD------VPRESYYIATKV----ARYELDY 110
            ::.:|.|:::|..:||||..|   ::|..:|.|::.      |.||..::.||:    .|.||
Mouse    35 LEAIHLALEAGFRHIDTAYVY---QTENHVGQAIRSKIAAGLVKREDIFLTTKLWCTFHRPEL-- 94

  Fly   111 DKMFDFSAKKTRESVEKSLKLLGLDYVDVIQIH-------------DIEFAKDL-DIV-INETLP 160
                      .|.::|||||.|.|||.|:..||             :.|..|.| |.| |..|..
Mouse    95 ----------VRSNLEKSLKNLQLDYADLYLIHYPVQMKPGEDLFPEDEHGKTLFDTVDICATWE 149

  Fly   161 TLEQLVKEGKARFIGVSAYPISVLKEFLTRTAGRLDTVLTY--ARYTLTDETLLEYLDFFKSQNL 223
            .:|:....|..:.||||.:....|::.|.:...:...|...  ....|....||.|.   ||::
Mouse   150 AMEKCKDAGLVKSIGVSNFNSRQLEKILNKPGLKYKPVCNQVECHLYLNQRKLLNYC---KSKD- 210

  Fly   224 GVICAAAHALGLLTNAGPQPW-HPAS----------DEQKAIARKASEVC----KERGVELGKLA 273
             ::..|..|||   :..|:.| .|:|          |..|...|..:::.    .:||:.:  ||
Mouse   211 -IVLVAYCALG---SQRPKRWVDPSSPVLLNDPILCDMAKKHKRSPAQIALRYHLQRGIVV--LA 269

  Fly   274 MYYTMSGLPEVSTFLTGMQTRQLLRINLDANEVGLSDKEQEVLRYLKENVLTKP 327
            ..|..:.:.|                |:...|..|..::.::|..|..|:...|
Mouse   270 QSYKENEIKE----------------NIQVFEFELPSEDMKILDSLDRNLRYAP 307

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG18547	NP_650138.1	AKR_galDH	22..314	CDD:381389	74/299 (25%)
Akr1c19	NP_001013807.2	AKR_AKR1C1-35	6..308	CDD:381334	78/314 (25%)