DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG18547 and Hk

DIOPT Version :9

Sequence 1:	NP_650138.1	Gene:	CG18547 / 41452	FlyBaseID:	FBgn0037973	Length:	345	Species:	Drosophila melanogaster
Sequence 2:	NP_001259401.1	Gene:	Hk / 31955	FlyBaseID:	FBgn0263220	Length:	887	Species:	Drosophila melanogaster

Alignment Length:	169	Identity:	47/169 - (27%)
Similarity:	79/169 - (46%)	Gaps:	16/169 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 HDEAKVRRMEYRNLGKTGLQVSKVSFGGGALCA-NYGFDLEEGIKTVHEAVKSGINYIDTAPWYG 77
            |.......:.|:||||:||::|.|..|...:.: ....|..|.|..:  |::||||..|.:
  Fly   195 HGSTPTPGLRYKNLGKSGLRISNVGLGTWPVFSPGVSDDQAEAILKL--AIESGINLFDIS---- 253

  Fly    78 QGRSEEVLGLALKDV--PRESYYIATKVARYELDYDKMFDFSAKKTRESVEKSLKLLGLDYVDVI 140
            :..||..:|..|:..  .|.:|.|.|||  |.....:....|.|...|.|..||:.|.|.|:|::
  Fly   254 EAHSETEIGKILQRAGWKRTAYVITTKV--YWSTKSEERGLSRKHIIECVRASLQRLQLQYIDIV 316

  Fly   141 QIHDIEFAKDLDIVINETLPTLEQLVKEGKARFIGVSAY 179
            .||..:....:::|     ..:..::::|.|.:.|.:.:
  Fly   317 IIHKADPMCPMEVV-----RAMSYVIQQGWAMYWGTARW 350

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18547	NP_650138.1	Tas	22..331	CDD:223739	46/161 (29%)
CG18547	NP_650138.1	Aldo_ket_red	24..321	CDD:294321	46/159 (29%)
Hk	NP_001259401.1	Kv_beta	205..531	CDD:213602	46/159 (29%)
Hk	NP_001259401.1	Aldo_ket_red	218..531	CDD:278668	38/146 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45468221
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0667
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0.985475	Normalized mean entropy	S2698
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm51451
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R634
SonicParanoid	0	0.000	Not matched by this tool.
	6	5.720