Protein Alignment CG18547 and Akr1c1

DIOPT Version :10

• Sequence 1: NP_650138.1
• Gene: CG18547 / 41452
• FlyBaseID: FBgn0037973
• Length: 345
• Species: Drosophila melanogaster
• Sequence 2: NP_001028869.1
• Gene: Akr1c1 / 307092
• RGDID: 1306847
• Length: 323
• Species: Rattus norvegicus
• Alignment Length: 306
• Identity: 77/306 - (25%)
• Similarity: 127/306 - (41%)
• Gaps: 87/306 - (28%)

  Fly    62 AVKSGINYIDTAPWYGQGRSEEVLGLALKD------VPRESYYIATKVARYELDYDKMFDFS-AK 119
            |:.:|..:||:|..|   ::|:.:|||::.      |.||..:..:||         ...|: .:
  Rat    41 AIDAGFRHIDSAAVY---QNEKEVGLAIRSKIADGTVKREDIFYTSKV---------WCTFNHPE 93

  Fly   120 KTRESVEKSLKLLGLDYVDVIQIH---------DIEFAKD------LDIV-INETLPTLEQLVKE 168
            :.:..:|:|||.|.|:|||:..||         |:: |||      .|:| |.:|...:|:....
  Rat    94 RVQVCLEQSLKQLQLEYVDLYLIHFPMALKPEEDLK-AKDENEKLLFDVVDICDTWKAMEKCKDA 157

  Fly   169 GKARFIGVSAYPISVLKEFLTRTAGRLDTVLTYAR-YTLTDETLLEYLDFFKSQNLGVICAAAHA 232
            |.|:.||||.:....|::.|.:...:...|..... :...::..|  |||.||::  ::..|..|
  Rat   158 GLAKSIGVSNFNRRQLEKILNKPGLKHRPVCNQVECHPYLNQRKL--LDFCKSKD--IVLVAYSA 218

  Fly   233 LG--------------------LLTNAGPQPWHPASDEQKAIARKASEVCKERGVELGKLAMYYT 277
            ||                    |...|....|.||     .||.:..   .||||.:  ||..:|
  Rat   219 LGSHRETRCVDKSLPVLLADPVLCAIAKKYNWTPA-----LIALRYQ---LERGVVV--LAKSFT 273

  Fly   278 MSGLPEVSTFLTGMQTRQLLRINLDANEVGLSDKEQEVLRYLKENV 323
            ...:.|                |:...|..|:.::.:||..|.:|:
  Rat   274 EKRIKE----------------NMQVFEFQLTSEDMKVLDGLNKNI 303

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG18547	NP_650138.1	AKR_galDH	22..314	CDD:381389	73/295 (25%)
Akr1c1	NP_001028869.1	AKR_AKR1C1-35	6..308	CDD:381334	77/306 (25%)