Protein Alignment CG18547 and Akr1b10

DIOPT Version :10

• Sequence 1: NP_650138.1
• Gene: CG18547 / 41452
• FlyBaseID: FBgn0037973
• Length: 345
• Species: Drosophila melanogaster
• Sequence 2: NP_001013102.1
• Gene: Akr1b10 / 296972
• RGDID: 1308277
• Length: 316
• Species: Rattus norvegicus
• Alignment Length: 312
• Identity: 72/312 - (23%)
• Similarity: 123/312 - (39%)
• Gaps: 85/312 - (27%)

  Fly    52 LEEGIKTVHEAVKSGINYIDTAPWYGQGRSEEVLGLAL------KDVPRESYYIATKVARYELDY 110
            ::|.:|.   |:.:|..:.|.|..|   ::|..:|.|:      |.|.||..:|.:|:      :
  Rat    28 VKEAVKA---AIDAGYRHFDCAYVY---QNESEVGEAIQEKIKEKAVRREDLFIVSKL------W 80

  Fly   111 DKMFDFSAKKTRESVEKSLKLLGLDYVDVIQIHDIE-FAKDLDIVINETLPT------------- 161
            ...|:.|..|  ::.:|:|..|.|||:|:..||..: |...     |..|||
  Rat    81 PTFFEKSLVK--KAFQKTLLDLKLDYLDLYLIHWPQGFQSG-----NVFLPTDDKGNVLTSKYTF 138

  Fly   162 ------LEQLVKEGKARFIGVSAYPISVLKEFLTRTAGRLDTVLTYAR---YTLTDETLLEYLDF 217
                  :|:||.:|..:.:|||.:....::..|.:...:...|.....   | ||.|.|::|
  Rat   139 LDAWEGMEELVDQGLVKALGVSNFNHFQIERLLNKPGLKHKPVTNQVECHPY-LTQEKLIQY--- 199

  Fly   218 FKSQNLGVICAAAHALGLLTNAGPQPWHPASDEQKAIARKASEVCKERGVELGKLAMYYTMSGLP 282
              ..:.|::..|...||.......:|..|...|...|...||:..|
  Rat   200 --CHSKGIVVTAYSPLGSPDRPSAKPEDPVLLEIPKIKEIASKHKK------------------- 243

  Fly   283 EVSTFLTGMQTRQLLRINLDANEVGLSDKEQEVLRYLKENVLTKPFDWEGNE 334
                  |..|.  |:|.:::.| |.:..|.....| ::||:  :.||::.:|
  Rat   244 ------TAAQV--LIRFHIERN-VAVIPKSVTPSR-IQENI--QVFDFQLSE 283

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG18547	NP_650138.1	AKR_galDH	22..314	CDD:381389	66/290 (23%)
Akr1b10	NP_001013102.1	AKR_AKR1B1-19	10..316	CDD:381333	72/312 (23%)