Protein Alignment CG18547 and mec-14

DIOPT Version :9

• Sequence 1: NP_650138.1
• Gene: CG18547 / 41452
• FlyBaseID: FBgn0037973
• Length: 345
• Species: Drosophila melanogaster
• Sequence 2: NP_498580.2
• Gene: mec-14 / 185423
• WormBaseID: WBGene00003176
• Length: 453
• Species: Caenorhabditis elegans
• Alignment Length: 350
• Identity: 147/350 - (42%)
• Similarity: 212/350 - (60%)
• Gaps: 14/350 - (4%)

  Fly     4 TLPATYVKGFHDEAKVRRMEYRNLGKTGLQVSKVSFGGGALCANYGFDLEEGIKTVHEAVKSGIN 68
            :||.||:..||||:.||||.||.:..|.:::||:.||..|:...:|...:..||.|..|:|.|||
 Worm    65 SLPVTYIPRFHDESAVRRMNYRQIPGTDIRMSKIGFGAAAIGGMFGNVEDSIIKIVETAIKQGIN 129

  Fly    69 YIDTAPWYGQGRSEEVLGLALKDVPRESYYIATKVARYELDYDKMFDFSAKKTRESVEKSLKLLG 133
            ||||..||.|.|||.:||.||..:||::|||:|||.|:||||.:.|||.|.|..||:..|||.|.
 Worm   130 YIDTGYWYSQSRSESILGKALSKIPRKAYYISTKVGRFELDYARTFDFRADKILESLTNSLKRLQ 194

  Fly   134 LDYVDV--IQIHDIEFAKDLDIVINETLPTLEQLVKEGKARFIGVSAYPISVLKEFLTRTAGRLD 196
            |.|:|:  :||||.:||.:..||:.|||..||.....||.|.||::.||:..|.:.:..:|.::|
 Worm   195 LTYIDICYVQIHDADFAPNESIVLYETLQALEMAKSSGKIRHIGLTGYPLGKLVQLVDCSATKID 259

  Fly   197 TVLTYARYTLTDETLLEYLDFFKSQNLGVICAAAHALGLLTNAGPQPWHPASDEQKAIARKASEV 261
            .|:||.:.||.:..|.::..:|:::|:.||.:.|...||||..||.||||||||.|.....|:..
 Worm   260 FVMTYCKGTLNNNALGQFTAWFQTRNIAVINSGALCWGLLTEKGPPPWHPASDEIKEACLAATTY 324

  Fly   262 CKERGVELGKLAMYYTMSGLPEVSTFLTGMQTRQLLRINLD-ANEVGLSDKEQEVLRYLKENVLT 325
            |..:.:.:.|||:.|.:: .|.|...|.||.:.|.:..||: :|...::|.||.|    ::.::.
 Worm   325 CSSKNISISKLALDYALN-FPNVICCLVGMDSVQQVLDNLELSNFSRITDVEQRV----RDRIMR 384

  Fly   326 KPFD------WEGNELEIYWAALKK 344
            :..|      |||.::..||..|||
 Worm   385 RYLDRLENAGWEGVDVAQYWKKLKK 409

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG18547	NP_650138.1	Tas	22..331	CDD:223739	128/317 (40%)
		Aldo_ket_red	24..321	CDD:294321	126/299 (42%)
mec-14	NP_498580.2	AKR_galDH	83..376	CDD:381389	124/293 (42%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160166261
Domainoid	1	1.000	220	1.000	Domainoid score	I1501
eggNOG	1	0.900	-	-		E1_COG0667
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	272	1.000	Inparanoid score	I1813
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57996
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0006717
OrthoInspector	1	1.000	-	-		otm14743
orthoMCL	1	0.900	-	-		OOG6_104231
Panther	1	1.100	-	-	LDO	PTHR42686
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R634
SonicParanoid	1	1.000	-	-		X6480
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	15	14.790