Protein Alignment CG18547 and Akr1c3

DIOPT Version :10

• Sequence 1: NP_650138.1
• Gene: CG18547 / 41452
• FlyBaseID: FBgn0037973
• Length: 345
• Species: Drosophila melanogaster
• Sequence 2: NP_612519.1
• Gene: Akr1c3 / 171516
• RGDID: 708428
• Length: 323
• Species: Rattus norvegicus
• Alignment Length: 339
• Identity: 79/339 - (23%)
• Similarity: 136/339 - (40%)
• Gaps: 70/339 - (20%)

  Fly    17 AKVRRMEYRNLGKTGLQVSKVSFGGGALCANYGFDLEEGIKTVHEAVKSGINYIDTAPWYGQGRS 81
            :|:::||..:    |..:..:.||..|...|.   .::.:::...|:..|..:||.:..|   ::
  Rat     3 SKIQKMELND----GHSIPVLGFGTYATEENL---RKKSMESTKIAIDVGFRHIDCSHLY---QN 57

  Fly    82 EEVLGLALKD------VPRESYYIATKV----ARYELDYDKMFDFSAKKTRESVEKSLKLLGLDY 136
            ||.:|.|:..      |.||..:..:|:    .|.||            .|.|:|.||:.|.|||
  Rat    58 EEEIGQAIVSKIEDGTVKREDIFYTSKLWSTSHRPEL------------VRPSLENSLRKLNLDY 110

  Fly   137 VDVIQIH--------DIEFAKD------LDIV-INETLPTLEQLVKEGKARFIGVSAYPISVLKE 186
            ||:..||        |....:|      ||.| :.:|...:|:....|.|:.||||.:....|::
  Rat   111 VDLYLIHFPVSLKPGDELLPQDEHGNLILDTVDLCDTWEAMEKCKDAGLAKSIGVSNFNRRQLEK 175

  Fly   187 FLTRTAGRLDTVLTY--ARYTLTDETLLEYLDFFKSQNLGVICAAAHALGLLTNAGPQPWHPASD 249
            .|.:...:...|...  ....|....||.|.   |..::.::     |.|.|   |.|.:....:
  Rat   176 ILNKPGLKHRPVCNQVECHLYLNQSKLLAYC---KMNDIVLV-----AYGAL---GTQRYKYCIN 229

  Fly   250 EQKAIARKASEVC---KERGVELGKLAMYYTMS-GLPE-VSTFLTGMQTRQLLRINLDANEVGLS 309
            |...:......:|   |:.......:|:.|.:. |:.. |.:|     ..:.:|.||...:..|:
  Rat   230 EDTPVLLDDPILCTMAKKYKRTPALIALRYQLERGIVTLVKSF-----NEERIRENLQVFDFQLA 289

  Fly   310 DKEQEVLRYLKENV 323
            ..:.|:|..|..|:
  Rat   290 SDDMEILDNLDRNL 303

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG18547	NP_650138.1	AKR_galDH	22..314	CDD:381389	74/323 (23%)
Akr1c3	NP_612519.1	AKR_AKR1C1-35	6..308	CDD:381334	78/336 (23%)