Protein Alignment CG18547 and AKR1C2

DIOPT Version :9

• Sequence 1: NP_650138.1
• Gene: CG18547 / 41452
• FlyBaseID: FBgn0037973
• Length: 345
• Species: Drosophila melanogaster
• Sequence 2: NP_001345.1
• Gene: AKR1C2 / 1646
• HGNCID: 385
• Length: 323
• Species: Homo sapiens
• Alignment Length: 311
• Identity: 79/311 - (25%)
• Similarity: 128/311 - (41%)
• Gaps: 81/311 - (26%)

  Fly    54 EGIKTVHEAVKSGINYIDTAPWYGQGRSEEVLGLALK------DVPRESYYIATKV----ARYEL 108
            :.::.|..|:::|.::||:|..|   .:||.:|||::      .|.||..:..:|:    .|.||
Human    33 KALEAVKLAIEAGFHHIDSAHVY---NNEEQVGLAIRSKIADGSVKREDIFYTSKLWSNSHRPEL 94

  Fly   109 DYDKMFDFSAKKTRESVEKSLKLLGLDYVDVIQIHDIEFAKDLDIVINE---------------T 158
                        .|.::|:|||.|.|||||:..||.....|..:.||.:               |
Human    95 ------------VRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVDLCAT 147

  Fly   159 LPTLEQLVKEGKARFIGVSAYPISVLKEFLTRTAGRLDTVLTYAR-YTLTDETLLEYLDFFKSQN 222
            ...:|:....|.|:.||||.:...:|:..|.:...:...|..... :...::..|  |||.||::
Human   148 WEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKYKPVCNQVECHPYFNQRKL--LDFCKSKD 210

  Fly   223 LGVICAAAHALGLLTNAGPQPW----HPASDEQK---AIARK--------ASEVCKERGVELGKL 272
              ::..|..|||   :...:||    .|...|..   |:|:|        |.....:|||.:  |
Human   211 --IVLVAYSALG---SHREEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVV--L 268

  Fly   273 AMYYTMSGLPEVSTFLTGMQTRQLLRINLDANEVGLSDKEQEVLRYLKENV 323
            |..|                ..|.:|.|:...|..|:.:|.:.:..|..||
Human   269 AKSY----------------NEQRIRQNVQVFEFQLTSEEMKAIDGLNRNV 303

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG18547	NP_650138.1	Tas	22..331	CDD:223739	79/311 (25%)
		Aldo_ket_red	24..321	CDD:294321	77/307 (25%)
AKR1C2	NP_001345.1	AKR_AKR1C1-35	6..308	CDD:381334	79/311 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165158410
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.840