Protein Alignment CG18547 and Akr1b8

DIOPT Version :10

• Sequence 1: NP_650138.1
• Gene: CG18547 / 41452
• FlyBaseID: FBgn0037973
• Length: 345
• Species: Drosophila melanogaster
• Sequence 2: NP_032038.1
• Gene: Akr1b8 / 14187
• MGIID: 107673
• Length: 316
• Species: Mus musculus
• Alignment Length: 295
• Identity: 66/295 - (22%)
• Similarity: 122/295 - (41%)
• Gaps: 51/295 - (17%)

  Fly    52 LEEGIKTVHEAVKSGINYIDTAPWYGQGRSEEVLGLAL------KDVPRESYYIATKVARYELDY 110
            ::|.:|.   |:.:|..:||.|..|   .:|..:|.|:      |.|.||..:|.:|:  :...:
Mouse    28 VKEAVKA---AIDAGYRHIDCAYAY---CNENEVGEAIQEKIKEKAVQREDLFIVSKL--WPTCF 84

  Fly   111 DKMFDFSAKKTRESVEKSLKLLGLDYVDVIQIH---DIEFAKDL-------DIVINETL-----P 160
            :|      |..:|:.:|:|..|.|||:|:..||   .::..|:|       .|:.::|.     .
Mouse    85 EK------KLLKEAFQKTLTDLKLDYLDLYLIHWPQGLQPGKELFPKDDQGRILTSKTTFLEAWE 143

  Fly   161 TLEQLVKEGKARFIGVSAYPISVLKEFLTRTAGRLDTVLTYAR---YTLTDETLLEYLDFFKSQN 222
            .:|:||.:|..:.:|||.:....::..|.:...:...|.....   | ||.|.|::|     ..:
Mouse   144 GMEELVDQGLVKALGVSNFNHFQIERLLNKPGLKHKPVTNQVECHPY-LTQEKLIQY-----CHS 202

  Fly   223 LGVICAAAHALGLLTNAGPQPWHPASDEQKAIARKASEVCKERGVELGKLAMYYTMSGLPEVSTF 287
            .|:...|...||.......:|..|:..|...|...|:   |........|..::....:..:...
Mouse   203 KGISVTAYSPLGSPDRPSAKPEDPSLLEDPKIKEIAA---KHEKTSAQVLIRFHIQRNVVVIPKS 264

  Fly   288 LTGMQTRQLLRINLDANEVGLSDKEQEVLRYLKEN 322
            :|..:.::    |:...:..|||:|...:.....|
Mouse   265 VTPSRIQE----NIQVFDFQLSDEEMATILSFNRN 295

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG18547	NP_650138.1	AKR_galDH	22..314	CDD:381389	65/285 (23%)
Akr1b8	NP_032038.1	AKR_AKR1B1-19	10..316	CDD:381333	66/295 (22%)