Protein Alignment CG18547 and Akr1c20

DIOPT Version :10

• Sequence 1: NP_650138.1
• Gene: CG18547 / 41452
• FlyBaseID: FBgn0037973
• Length: 345
• Species: Drosophila melanogaster
• Sequence 2: NP_001298061.1
• Gene: Akr1c20 / 116852
• MGIID: 2151104
• Length: 323
• Species: Mus musculus
• Alignment Length: 298
• Identity: 73/298 - (24%)
• Similarity: 123/298 - (41%)
• Gaps: 71/298 - (23%)

  Fly    62 AVKSGINYIDTAPWYGQGRSEEVLGLALKD------VPRESYYIATKV----ARYELDYDKMFDF 116
            |:.:|..:||.|..|   ::|:.:|||::.      |.||..:..:||    .|.||
Mouse    41 AIDAGFRHIDCAAVY---QNEKEVGLAIRSKIVDGTVKREDIFCTSKVWQTFHRPEL-------- 94

  Fly   117 SAKKTRESVEKSLKLLGLDYVDVIQIH--------DIEFAKD------LDIV-INETLPTLEQLV 166
                .:..:|:|||.|.|||||:..||        :..|.||      .|.| |.:|...:|:..
Mouse    95 ----VQVCLEQSLKQLQLDYVDLYLIHFPIAMKPGENYFPKDENGKFIYDAVDICDTWEAMEKCK 155

  Fly   167 KEGKARFIGVSAYPISVLKEFLTRTAGRLDTVLTYAR-YTLTDETLLEYLDFFKSQNLGVICAAA 230
            ..|.|:.|||..:....|::.|::...:...|..... :...::..|  |||.:|::  ::..|.
Mouse   156 DAGLAKSIGVCNFNRRQLEKILSKPGLKYKPVCNQVECHPYLNQRKL--LDFCRSKD--IVLVAH 216

  Fly   231 HALGLLTNAGPQPWHPASDEQKAIARKASEVCKERGVELGKLAMYYTMSGLPEVSTFLTGMQ--- 292
            .|||             |:..|....|:..|..:..| ||.:|..|..:  |.:......:|
Mouse   217 SALG-------------SNRDKEWVDKSFPVLLDDPV-LGSMAKKYNRT--PALIALRYQVQRGV 265

  Fly   293 -------TRQLLRINLDANEVGLSDKEQEVLRYLKENV 323
                   ..:.::.|:...|..|:..:.:||..|.:|:
Mouse   266 VVLAKSFIEKRIKENMQVFEFQLTSVDMKVLDGLNKNI 303

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG18547	NP_650138.1	AKR_galDH	22..314	CDD:381389	69/287 (24%)
Akr1c20	NP_001298061.1	AKR_AKR1C1-35	6..306	CDD:381334	73/298 (24%)