DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18547 and Akr7a5

DIOPT Version :9

Sequence 1:	NP_650138.1	Gene:	CG18547 / 41452	FlyBaseID:	FBgn0037973	Length:	345	Species:	Drosophila melanogaster
Sequence 2:	NP_079613.3	Gene:	Akr7a5 / 110198	MGIID:	107796	Length:	367	Species:	Mus musculus

Alignment Length:	305	Identity:	80/305 - (26%)
Similarity:	114/305 - (37%)	Gaps:	71/305 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    51 DLEEGIKTVHEAVKSGINYIDTAPWYGQGRSEEV-----LGLALKDVPRESYYIATKVARYE--- 107
            |......:|...::.|.:.:|||..|..|:||.:     |||...|.   :..||||...:|
Mouse    60 DASASAASVRAFLERGHSELDTAFMYCDGQSENILGGLGLGLGSGDC---TVKIATKANPWEGKS 121

  Fly   108 LDYDKMFDFSAKKTRESVEKSLKLLGLDYVDVIQIHDIEFAKDLDIVINETLPTLEQLVKEGKAR 172
            |..|.:        |..:|.|||.|....||:..:|    |.|....:.|||....||.:|||..
Mouse   122 LKPDSI--------RSQLETSLKRLQCPRVDLFYLH----APDHSTPVEETLRACHQLHQEGKFV 174

  Fly   173 FIGVSAYPISVLKEFLT--RTAGRLDTVLTYARYTLT----DETLLEYLDFFKSQNLGVICAAAH 231
            .:|:|.|....:.|..|  ::.|.:...:....|..|    :..||..|..|     |:...|.:
Mouse   175 ELGLSNYASWEVAEICTLCKSNGWILPTVYQGMYNATTRQVEAELLPCLRHF-----GLRFYAYN 234

  Fly   232 AL--GLLTNA-------GPQP-----------------WHPASDEQKAIARKASEVCKERGVELG 270
            .|  ||||..       |.||                 |.....|..|:..||.:.  ..|....
Mouse   235 PLAGGLLTGKYKYEDKDGKQPVGRFFGNNWAETYRNRFWKEHHFEAIALVEKALQT--TYGTNAP 297

  Fly   271 KLA------MYY--TMSGLPEVSTFLTGMQTRQLLRINLDANEVG 307
            ::.      ||:  .:.|....:..| ||.:.:.|..||.|.|.|
Mouse   298 RMTSAALRWMYHHSQLQGTRGDAVIL-GMSSLEQLEQNLAATEEG 341

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18547	NP_650138.1	Tas	22..331	CDD:223739	80/305 (26%)
CG18547	NP_650138.1	Aldo_ket_red	24..321	CDD:294321	80/305 (26%)
Akr7a5	NP_079613.3	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..45
		Tas	46..363	CDD:223739	80/305 (26%)
		Aldo_ket_red	46..354	CDD:119408	80/305 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0667
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900