DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Tango9 and slc35f6

DIOPT Version :9

Sequence 1:	NP_001303462.1	Gene:	Tango9 / 41450	FlyBaseID:	FBgn0260744	Length:	381	Species:	Drosophila melanogaster
Sequence 2:	NP_001002559.1	Gene:	slc35f6 / 436832	ZFINID:	ZDB-GENE-040718-297	Length:	374	Species:	Danio rerio

Alignment Length:	348	Identity:	118/348 - (33%)
Similarity:	180/348 - (51%)	Gaps:	28/348 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 HRVFLSLIFVLSGTFNVLVVKWANQQQVIGSDGKL-HGFQHPVVFTLLMFLGEFLCFAVFKVIRL 66
            :::||:.:.:.:|:.|.|..|||:.....|..|.. |.|.||.|..:.|||||..|..||.:: |
Zfish     6 YQLFLAGLMLTTGSLNTLSAKWADMFSAPGCHGSPDHDFSHPFVQAVGMFLGELSCLVVFYIL-L 69

  Fly    67 ISNRRGVISDLDSILSQDSSEFRPVSMLLPTLLDAAASILLFTGLYLTYATSFQMIRGAALIFVG 131
            ..:||.....:|     ....|.|:..|.|.|.|...:.:::..|.:|.|:||||:|||.:||.|
Zfish    70 CHDRRRPEPTMD-----PGESFNPLVFLPPALCDMLGTSIMYVALNMTSASSFQMLRGAVIIFTG 129

  Fly   132 IFSTMFLNHTLTGRHWLAIF-----TISCGLLDIIS---LDVHRVEYDLVTLPYTDYKSILTGDL 188
            :.|..||...|....|..|.     .:..||.|.:|   .|.|::            ..|:||||
Zfish   130 LLSVAFLGRRLKPSQWFGILITILGLVVVGLADFVSGHGDDSHKL------------SEIITGDL 182

  Fly   189 LIIIAEILHGLQYVCEEKQLKTSNVAPLQAAGWQGIFGLGITSMLAICMNFLPSIDPFSCSSRAV 253
            |||:|:|:..:|.|.|||.:...||.||:|.|.:|:||..|.|:|.|.|.|: .:..|:.:.|.|
Zfish   183 LIIMAQIVVAVQMVLEEKFVYKHNVHPLKAVGTEGVFGFVILSLLLIPMFFI-HVGSFADNPRQV 246

  Fly   254 FDDWGDLFAALQGSISLIMTLIAFTISCAMYNFIGLYIAMYSSSANRLLADGLRVYFIWVFVIIM 318
            .:|..|.|..:.....:::.|:..|:|.|.:||.|:.:....|:..|::.|.||...|||..:.:
Zfish   247 LEDALDAFCQIGHKPLILLALLGNTVSIAFFNFAGISVTKEISATTRMVLDSLRTLVIWVVSLAL 311

  Fly   319 EWEYMNLVTIMGFLILQMGIILY 341
            .||....:.|:||:||.:|..:|
Zfish   312 GWEKFQGLQILGFIILLLGTAMY 334

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Tango9	NP_001303462.1	None
slc35f6	NP_001002559.1	SLC35F	<95..334	CDD:283644	86/251 (34%)
slc35f6	NP_001002559.1	EamA	<100..160	CDD:279264	19/59 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170594812
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0697
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	189	1.000	Inparanoid score	I3887
OMA	1	1.010	-	-		QHG56395
OrthoDB	1	1.010	-	-		D1169953at2759
OrthoFinder	1	1.000	-	-		FOG0006532
OrthoInspector	1	1.000	-	-		oto40830
orthoMCL	1	0.900	-	-		OOG6_101110
Panther	1	1.100	-	-	LDO	PTHR13146
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R10498
SonicParanoid	1	1.000	-	-		X5508
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	14	13.800