DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Tango9 and SLC35F1

DIOPT Version :9

Sequence 1:	NP_001303462.1	Gene:	Tango9 / 41450	FlyBaseID:	FBgn0260744	Length:	381	Species:	Drosophila melanogaster
Sequence 2:	NP_001025029.2	Gene:	SLC35F1 / 222553	HGNCID:	21483	Length:	408	Species:	Homo sapiens

Alignment Length:	355	Identity:	79/355 - (22%)
Similarity:	143/355 - (40%)	Gaps:	71/355 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    51 FLGEFLCFAVFKVIRLISNRRGVISDLDSILSQDSSEFRPVSMLLPTLLDAAASILLFTGLYLTY 115
            ||...|.|.|:..  .::.|:|. .:|.:||.:     |....::..|:|..|:.|:......|.
Human    98 FLNYILLFLVYTT--TLAVRQGE-ENLLAILRR-----RWWKYMILGLIDLEANYLVVKAYQYTT 154

  Fly   116 ATSFQMIRGAALIFVGIFSTMFLNHTLTGRHWLAIFTISCGLLDIISLDVHRVEYDLVTLPYTDY 180
            .||.|::....:..|.:.|..||.......|::.|.....|:..::..||      ||.......
Human   155 LTSIQLLDCFVIPVVILLSWFFLLIRYKAVHFIGIVVCILGMGCMVGADV------LVGRHQGAG 213

  Fly   181 KSILTGDLLIIIAEILHGLQYVCEEKQLKTSNVAPLQAAGWQGIFGLGITSMLAICMNFLPSID- 244
            ::.|.||||::....|:|:..|.||..::|  ::.::..|..|:||...:.:....|.....:.
Human   214 ENKLVGDLLVLGGATLYGISNVWEEYIIRT--LSRVEFLGMIGLFGAFFSGIQLAIMEHKELLKV 276

  Fly   245 PFSCSSRAVFDDWGDLFAALQGSISLIMTLIAFTISC--AMYNFIGLYIAMYSSSA---NRLLAD 304
            |:         ||         .|.|:  .:.|: :|  .:|:|:.:.|...|:::   :.|.||
Human   277 PW---------DW---------QIGLL--YVGFS-ACMFGLYSFMPVVIKKTSATSVNLSLLTAD 320

  Fly   305 GLRVYFIWVFVIIMEWEYMNLVTIMGFLILQMGIILYRQALFLDWYRAAVARWYR---------- 359
               :|.::..:.:..:::..|..:..|.|| :|::||...   ..|.|...|.|:
Human   321 ---LYSLFCGLFLFHYKFSGLYLLSFFTIL-IGLVLYSST---STYIAQDPRVYKQFRNPSGPVV 378

  Fly   360 -----------ARYVDLGTENAAAPNSRPA 378
                       ..|..||.|....|:.|.|
Human   379 DLPTTAQVEPSVTYTSLGQETEEEPHVRVA 408

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Tango9	NP_001303462.1	None
SLC35F1	NP_001025029.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..21
SLC35F1	NP_001025029.2	SLC35F	56..355	CDD:283644	68/297 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0697
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810