DRSC/TRiP Functional Genomics Resources

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Protein Alignment GC2 and Slc25a22

DIOPT Version :9

Sequence 1:NP_731657.2 Gene:GC2 / 41449 FlyBaseID:FBgn0037970 Length:319 Species:Drosophila melanogaster
Sequence 2:NP_001171047.1 Gene:Slc25a22 / 68267 MGIID:1915517 Length:323 Species:Mus musculus


Alignment Length:312 Identity:164/312 - (52%)
Similarity:212/312 - (67%) Gaps:26/312 - (8%)


- Green bases have known domain annotations that are detailed below.


  Fly    23 KIINGGVAGIIGVACVYPLDMVKTRLQNQTIGPNGERMYTSIADCFRKTIASEGYFGMYRGSAVN 87
            |:||||:||:|||.||:|:|:.|||||||   .||:|||.|::||..|||.||||||||||:|||
Mouse    11 KLINGGIAGLIGVTCVFPIDLAKTRLQNQ---QNGQRMYASMSDCLIKTIRSEGYFGMYRGAAVN 72

  Fly    88 IVLITPEKAIKLTANDFFRYHLASDDGVIPLSRATLAGGLAGLFQIVVTTPMELLKIQMQDAGRV 152
            :.|:||||||||.||||||:.|:.|...:.|.:..|||..||..|::||||||:||||:|||||:
Mouse    73 LTLVTPEKAIKLAANDFFRHQLSKDGQKLTLPKEMLAGCGAGTCQVIVTTPMEMLKIQLQDAGRI 137

  Fly   153 AAADR---------AAGREVKTI--------TALGLTKTLLRERGIFGLYKGVGATGVRDITFSM 200
            ||..:         |.|....::        ||..||:.|||..||.|||||:|||.:||:.||:
Mouse   138 AAQRKILAAQAQLSAQGGAQPSVEAPAPPRPTATQLTRDLLRNHGIAGLYKGLGATLLRDVPFSI 202

  Fly   201 VYFPLMAWINDQGPRKSDGSGEAVFYWSLIAGLLSGMTSAFMVTPFDVVKTRLQA----DGEKKF 261
            |||||.|.:|..|...|:  .::.||.|.:||.::|..:|..|.|.||||||||:    ..|..:
Mouse   203 VYFPLFANLNQLGRPSSE--EKSPFYVSFLAGCVAGSAAAVAVNPCDVVKTRLQSLERGVNEDTY 265

  Fly   262 KGIMDCVNRTLKEEGISAFFKGGLCRIMVLAPLFGIAQMFYFLGVGEKILGI 313
            .|.:||..:..:.||.|||.||..||.:|:||||||||:.||||:.|.:||:
Mouse   266 SGFLDCARKIWRHEGPSAFLKGAYCRALVIAPLFGIAQVVYFLGIAESLLGL 317

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
GC2NP_731657.2 PTZ00169 14..289 CDD:240302 148/286 (52%)
Mito_carr 16..106 CDD:278578 58/82 (71%)
Mito_carr 123..203 CDD:278578 47/96 (49%)
Mito_carr 228..302 CDD:278578 37/77 (48%)
Slc25a22NP_001171047.1 PTZ00169 3..289 CDD:240302 146/282 (52%)
Mito_carr 6..96 CDD:365909 61/87 (70%)
Solcar 1 6..93 60/84 (71%)
Solcar 2 101..214 54/112 (48%)
Solcar 3 223..312 43/88 (49%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 1 1.000 137 1.000 Domainoid score I4855
eggNOG 1 0.900 - - E1_KOG0750
Hieranoid 1 1.000 - -
Homologene 00.000 Not matched by this tool.
Inparanoid 1 1.050 354 1.000 Inparanoid score I2232
Isobase 1 0.950 - 0.878984 Normalized mean entropy S1412
OMA 1 1.010 - - QHG53612
OrthoDB 1 1.010 - - D458796at33208
OrthoFinder 1 1.000 - - FOG0002230
OrthoInspector 1 1.000 - - mtm8687
orthoMCL 1 0.900 - - OOG6_104895
Panther 1 1.100 - - O PTHR45678
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 1 1.000 - - X982
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 1 0.960 - -
1413.790

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