DRSC/TRiP Functional Genomics Resources

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Protein Alignment GC2 and slc25a12

DIOPT Version :10

Sequence 1:NP_731657.2 Gene:GC2 / 41449 FlyBaseID:FBgn0037970 Length:319 Species:Drosophila melanogaster
Sequence 2:XP_012825898.1 Gene:slc25a12 / 549674 XenbaseID:XB-GENE-1002100 Length:668 Species:Xenopus tropicalis


Alignment Length:281 Identity:117/281 - (41%)
Similarity:166/281 - (59%) Gaps:18/281 - (6%)


- Green bases have known domain annotations that are detailed below.


  Fly    27 GGVAGIIGVACVYPLDMVKTRLQNQTIGPNGERMYTSIADCFRKTIASEGYFGMYRGSAVNIVLI 91
            |.:||.:|...|||:|:||||:|||.....||.||.:..|||:|.:..||:||:|||....:|.:
 Frog   332 GSIAGAVGATAVYPIDLVKTRMQNQRSSFVGELMYKNSFDCFKKVLRYEGFFGLYRGLLPQLVGV 396

  Fly    92 TPEKAIKLTANDFFRYHLASDDGVIPLSRATLAGGLAGLFQIVVTTPMELLKIQMQDAGRVAAAD 156
            .||||||||.|||.|......||.|||....:|||.||..|::.|.|:|::||::|.||.::...
 Frog   397 APEKAIKLTVNDFVRDKFTQKDGSIPLLAEIMAGGCAGGSQVIFTNPLEIVKIRLQVAGEISTGP 461

  Fly   157 RAAGREVKTITALGLTKTLLRERGIFGLYKGVGATGVRDITFSMVYFPLMAWINDQGPRKSDGSG 221
            :        ::||    |:|::.||.|||||..|..:|||.||.:|||:.|...   ...:|..|
 Frog   462 K--------VSAL----TVLQDLGILGLYKGAKACFLRDIPFSAIYFPVYAHCK---TLLADEQG 511

  Fly   222 EAVFYWSLIAGLLSGMTSAFMVTPFDVVKTRLQA---DGEKKFKGIMDCVNRTLKEEGISAFFKG 283
            .......|.||.::|:.:|.:|||.||:|||||.   .|:..:.|::||..:.|:|||..|.:||
 Frog   512 HIGALQLLTAGAIAGVPAASLVTPADVIKTRLQVAARAGQTTYTGVIDCFRKILQEEGGRALWKG 576

  Fly   284 GLCRIMVLAPLFGIAQMFYFL 304
            ...|:...:|.||:..:.|.|
 Frog   577 AGARVFRSSPQFGVTLVTYEL 597

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
GC2NP_731657.2 Mito_carr 16..106 CDD:395101 42/78 (54%)
Mito_carr 123..203 CDD:395101 31/79 (39%)
Mito_carr 228..302 CDD:395101 30/76 (39%)
slc25a12XP_012825898.1 EFh_PEF 13..184 CDD:355382
EF-hand_7 13..78 CDD:463900
EF-hand motif 13..46 CDD:320055
EF-hand motif 54..91 CDD:320055
EF-hand motif 92..123 CDD:320055
EF-hand motif 130..156 CDD:320055
EF-hand motif 160..184 CDD:320055
Mito_carr 326..417 CDD:395101 43/84 (51%)
Mito_carr 419..506 CDD:395101 39/101 (39%)
Mito_carr 511..603 CDD:395101 33/87 (38%)
Blue background indicates that the domain is not in the aligned region.

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