DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment GC2 and CG7943

DIOPT Version :9

Sequence 1:NP_731657.2 Gene:GC2 / 41449 FlyBaseID:FBgn0037970 Length:319 Species:Drosophila melanogaster
Sequence 2:NP_651766.1 Gene:CG7943 / 43574 FlyBaseID:FBgn0039741 Length:332 Species:Drosophila melanogaster


Alignment Length:286 Identity:56/286 - (19%)
Similarity:104/286 - (36%) Gaps:52/286 - (18%)


- Green bases have known domain annotations that are detailed below.


  Fly    23 KIINGGV-------------------AGIIGVACVYPLDMVKTRLQNQTIGPNGERMYTSIADCF 68
            |:::|.|                   |..:.:|..||:  .|...:....|       ..|...|
  Fly    37 KLLHGSVFSKRFFGSFQWEEFACGCGAAFVNIAVTYPI--YKMIFRQMLHG-------VPITSAF 92

  Fly    69 RKTIASEGYFGMYRGSAVNIVLITPEKAIKLTANDFFRYHLASDDGVIPLSRATLAGGLAGLFQI 133
            .: :..||...:|||....:...|...:|.....|..|.:|..|..:.......||..:||..:.
  Fly    93 AQ-LRHEGLGFLYRGMLPPLAQKTISLSIMFGVFDGTRRYLVEDYRLNDYGAKVLAAVVAGSAES 156

  Fly   134 VVTTPMELLKIQMQDAGRVAAADRAAGREVKTITALGLTKTLLR----ERGIFGLYKGVGATGVR 194
            :: .|.|.::..:.|:              |.......|:...|    ..|...||:|:.....|
  Fly   157 IL-LPFERVQTLLADS--------------KFHQHFSNTQNAFRYVVSHHGYRELYRGLEPVFWR 206

  Fly   195 DITFSMVYFPLMAWINDQGPRKSDGSGEAVFYWSLIAGLLSGMTSAFMVTPFDVVKTRLQADGEK 259
            :...:.::|.|....:.:.|::...|...|  ...|||.:.|.:.:.:..|.:|:|..||::..:
  Fly   207 NGLSNALFFVLREEASVRLPKRKSVSTRTV--QEFIAGAVIGASISTIFYPLNVIKVSLQSEMGQ 269

  Fly   260 KFKGIMDCVNRTL--KEEGISAFFKG 283
            :.:|......|..  ::..|..|::|
  Fly   270 RSEGSWQACKRIYVERDRRIGNFYRG 295

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
GC2NP_731657.2 PTZ00169 14..289 CDD:240302 56/286 (20%)
Mito_carr 16..106 CDD:278578 19/101 (19%)
Mito_carr 123..203 CDD:278578 15/83 (18%)
Mito_carr 228..302 CDD:278578 14/58 (24%)
CG7943NP_651766.1 Mito_carr 54..136 CDD:278578 18/91 (20%)
Mito_carr 141..229 CDD:278578 18/102 (18%)
Mito_carr 235..322 CDD:278578 15/63 (24%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C45442030
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
10.930

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