Protein Alignment GC2 and Tpc2

DIOPT Version :10

• Sequence 1: NP_731657.2
• Gene: GC2 / 41449
• FlyBaseID: FBgn0037970
• Length: 319
• Species: Drosophila melanogaster
• Sequence 2: NP_001246511.1
• Gene: Tpc2 / 37983
• FlyBaseID: FBgn0035078
• Length: 323
• Species: Drosophila melanogaster
• Alignment Length: 321
• Identity: 90/321 - (28%)
• Similarity: 137/321 - (42%)
• Gaps: 76/321 - (23%)

  Fly    25 INGGVAGIIGVACVYPLDMVKTRLQNQTIGP----NGERMYTSIADCFRKTIASEGYFGMYRGSA 85
            :.||:||........|||::|.|.|.| :.|    .|.: |..:...|:...|.||..||:||..
  Fly    14 VGGGIAGAATRTITQPLDVLKIRFQMQ-VEPVTNHKGSK-YRGVIHAFKSVYAEEGMRGMFRGHN 76

  Fly    86 VNIVLITPEKAIKLTANDFFRY-------HLASDDGVIPLSRATLAGGLAGLFQIVVTTPMELLK 143
            ...||     :|......|:.|       |........|.....:.||:||....|...|.::::
  Fly    77 SGQVL-----SISYALVQFWSYEQLRSMAHQFDYWRERPFLMFFICGGIAGCLGAVAAQPFDVVR 136

  Fly   144 IQMQDAGRVAAADRAAGR-EVKTITALGLTKTLLRERGIFGLYKGVGATGV-RDITFSMV-YFPL 205
            .||      .|||.::.| ::.|.|  ||.|          :||..|..|: |.:.|::| .|||
  Fly   137 TQM------VAADPSSRRSQMNTFT--GLRK----------VYKMEGWMGLSRGLPFTLVQVFPL 183

  Fly   206 MA-------WIN---------DQGPRKSDGSGEAVFYWSLIAGLLSGMTSAFMVTPFDVVKTRLQ 254
            :.       ::|         ||   :.:..|..:|    :.|.|||:.:..:|.|.|::|.|:|
  Fly   184 VGANFLFYKYLNAAVLMAKPPDQ---RQEIHGAFLF----LNGALSGVLAKMIVYPADLLKKRIQ 241

  Fly   255 A---DGEKKFKG-------IMDCVNRTLKEEGISAFFKGGLCRI----MVLAPLFGIAQMF 301
            .   ..|:|..|       |:.|:..|.:||||..|:||.|..:    ::.|..|.|..||
  Fly   242 LMAFKQERKTFGRNPECPTILGCITTTFREEGIGGFYKGMLPTLLKAGLMSAVYFSIYDMF 302

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GC2	NP_731657.2	Mito_carr	16..106	CDD:395101	26/84 (31%)
		Mito_carr	123..203	CDD:395101	24/82 (29%)
		Mito_carr	228..302	CDD:395101	29/88 (33%)
Tpc2	NP_001246511.1	Mito_carr	23..99	CDD:395101	23/82 (28%)
		Mito_carr	108..194	CDD:395101	28/103 (27%)
		Mito_carr	216..307	CDD:395101	30/91 (33%)