Protein Alignment GC2 and SLC25A47

DIOPT Version :10

• Sequence 1: NP_731657.2
• Gene: GC2 / 41449
• FlyBaseID: FBgn0037970
• Length: 319
• Species: Drosophila melanogaster
• Sequence 2: NP_997000.2
• Gene: SLC25A47 / 283600
• HGNCID: 20115
• Length: 308
• Species: Homo sapiens
• Alignment Length: 297
• Identity: 89/297 - (29%)
• Similarity: 143/297 - (48%)
• Gaps: 50/297 - (16%)

  Fly    25 INGGVAGIIGVACVYPLDMVKTRLQNQTIGPNGERMYTSIADCFRKTIASEGYFGMYRGSAVNIV 89
            :.|.:.|:.|||..||||.||.|:|.       |..||.|..|.|.|...|..:|.|||.::.:.
Human     4 VAGAIGGVCGVAVGYPLDTVKVRIQT-------EPKYTGIWHCVRDTYHRERVWGFYRGLSLPVC 61

  Fly    90 LITPEKAIKLTANDFFRYHLA--------SDDGVIPLSRATLAGGLAGLFQIVVTTPMELLKIQM 146
            .::...::....   :|:.||        :.|.....:..||:|..:||.::.:|:|.|:.|:::
Human    62 TVSLVSSVSFGT---YRHCLAHICRLRYGNPDAKPTKADITLSGCASGLVRVFLTSPTEVAKVRL 123

  Fly   147 QDAGRVAAADR---AAG--------------REVKTITALGLTKTLLRERGIFGLYKGVGATGVR 194
            |...:.....|   |:|              .|.|....|....|:.||.|:.|||||..|..:|
Human   124 QTQTQAQKQQRRLSASGPLAVPPMCPVPPACPEPKYRGPLHCLATVAREEGLCGLYKGSSALVLR 188

  Fly   195 D----ITFSMVYFPLMAWINDQGPRKSDGSGEAVFYWSLIAGLLSGMTSAFMVTPFDVVKTRLQA 255
            |    .|:.:.|..|..|::..|..:.|..|      .|:||..:|:.:..:.||.||:|:||||
Human   189 DGHSFATYFLSYAVLCEWLSPAGHSRPDVPG------VLVAGGCAGVLAWAVATPMDVIKSRLQA 247

  Fly   256 D--GEKKFKGIMDCVNRTLKEEGISAFFKG---GLCR 287
            |  |:::::|::.|:..:::|||....|||   ..||
Human   248 DGQGQRRYRGLLHCMVTSVREEGPRVLFKGLVLNCCR 284

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GC2	NP_731657.2	Mito_carr	16..106	CDD:395101	25/80 (31%)
		Mito_carr	123..203	CDD:395101	28/100 (28%)
		Mito_carr	228..302	CDD:395101	25/65 (38%)
SLC25A47	NP_997000.2	Solcar 1	1..80		27/85 (32%)
		Mito_carr	2..77	CDD:395101	26/82 (32%)
		Solcar 2	93..206		31/112 (28%)
		Mito_carr	100..208	CDD:395101	31/107 (29%)
		Solcar 3	215..302		27/76 (36%)
		Mito_carr	221..302	CDD:395101	25/64 (39%)