Protein Alignment GC2 and SLC25A30

DIOPT Version :10

• Sequence 1: NP_731657.2
• Gene: GC2 / 41449
• FlyBaseID: FBgn0037970
• Length: 319
• Species: Drosophila melanogaster
• Sequence 2: XP_005266378.1
• Gene: SLC25A30 / 253512
• HGNCID: 27371
• Length: 293
• Species: Homo sapiens
• Alignment Length: 273
• Identity: 69/273 - (25%)
• Similarity: 113/273 - (41%)
• Gaps: 34/273 - (12%)

  Fly    25 INGGVAGIIGVACVYPLDMVKTRLQNQTIGPNGERMYTSIADCFRKTI-------ASEGYFGMYR 82
            :.||:|.|......:|:|:.|||||.|  |...:..:..|.  :|..:       ..||...:|.
Human    10 VYGGLASITAECGTFPIDLTKTRLQIQ--GQTNDAKFKEIR--YRGMLHALVRIGREEGLKALYS 70

  Fly    83 GSAVNIVLITPEKAIKL-TANDFFRYHL-ASDDGVIPLSRATLAGGLAGLFQIVVTTPMELLKIQ 145
            |.|..::.......||: |.....|..: ..:|..:|::  .:.|.|:|:....:..|.::|||:
Human    71 GIAPAMLRQASYGTIKIGTYQSLKRLFIERPEDETLPIN--VICGILSGVISSTIANPTDVLKIR 133

  Fly   146 MQDAGRVAAADRAAGREVKTITALGLTKTLLRERGIFGLYKGVGATGVRDITFSMVYFPLMAWIN 210
            ||     |.::...|      ..:|....:.::.|..||:|||..|..|......|..|:.. |.
Human   134 MQ-----AQSNTIQG------GMIGNFMNIYQQEGTRGLWKGVSLTAQRAAIVVGVELPVYD-IT 186

  Fly   211 DQGPRKSDGSGEAVFYWSLIAGLLSGMTSAFMVTPFDVVKTRLQ-----ADGE-KKFKGIMDCVN 269
            .:....|...|:.| |...::....|:..|....|.|||:||:.     .||. ..:.|.:||:.
Human   187 KKHLILSGLMGDTV-YTHFLSSFTCGLAGALASNPVDVVRTRMMNQRVLRDGRCSGYTGTLDCLL 250

  Fly   270 RTLKEEGISAFFK 282
            :....|..|...|
Human   251 QLTVLESFSTTAK 263

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GC2	NP_731657.2	Mito_carr	16..106	CDD:395101	23/88 (26%)
		Mito_carr	123..203	CDD:395101	21/79 (27%)
		Mito_carr	228..302	CDD:395101	16/61 (26%)
SLC25A30	XP_005266378.1	Mito_carr	5..100	CDD:395101	24/93 (26%)
		Mito_carr	102..191	CDD:395101	25/102 (25%)
		Mito_carr	199..>252	CDD:395101	15/53 (28%)