Protein Alignment GC2 and slc-25A18.2

DIOPT Version :9

• Sequence 1: NP_731657.2
• Gene: GC2 / 41449
• FlyBaseID: FBgn0037970
• Length: 319
• Species: Drosophila melanogaster
• Sequence 2: NP_501198.1
• Gene: slc-25A18.2 / 177518
• WormBaseID: WBGene00018901
• Length: 309
• Species: Caenorhabditis elegans
• Alignment Length: 317
• Identity: 156/317 - (49%)
• Similarity: 212/317 - (66%)
• Gaps: 24/317 - (7%)

  Fly    10 QEQKKPQKFNVFPKIINGGVAGIIGVACVYPLDMVKTRLQNQTIGPNGERMYTSIADCFRKT--I 72
            ||:::.|.....||::|||::||:||:||:|:|:||||||||    .|...||.|||||:|:  .
 Worm    10 QEEREEQPIRYLPKVLNGGISGIVGVSCVFPMDLVKTRLQNQ----KGTSKYTGIADCFKKSWQA 70

  Fly    73 ASEGYF----GMYRGSAVNIVLITPEKAIKLTANDFFRYHLASD-DGVIPLSRATLAGGLAGLFQ 132
            .:.|..    |||:|::|||.||||||||||.||||||:.|..| |..:...|..:||..||..|
 Worm    71 GAPGRLNQIKGMYQGASVNIFLITPEKAIKLVANDFFRHALMKDHDERLSTPRGMIAGASAGFCQ 135

  Fly   133 IVVTTPMELLKIQMQDAGRVAAADRAAGREVKTITALGLTKTLLRERGIFGLYKGVGATGVRDIT 197
            :|:|||||||||:||.     ::|:.  :..|.|..|     |.::.|:..||||:|.|..||::
 Worm   136 VVITTPMELLKIRMQQ-----SSDKV--KATKLIWNL-----LTKDGGVRALYKGLGPTMARDVS 188

  Fly   198 FSMVYFPLMAWINDQGPRKSDGSGEAVFYWSLIAGLLSGMTSAFMVTPFDVVKTRLQADGEKKFK 262
            ||.:||||.|:::..||||.|.||:|||:.|.::||.:|.|::..|||.||||||:|..| ..:.
 Worm   189 FSAMYFPLFAYLDGLGPRKKDDSGDAVFWASFVSGLTAGATASLSVTPLDVVKTRIQTGG-SNYN 252

  Fly   263 GIMDCVNRTLKEEGISAFFKGGLCRIMVLAPLFGIAQMFYFLGVGEKILGIERTKSV 319
            ||.....|.|.:||:.|.|||.:||:||:||||||||..|::|..|||||:|:...|
 Worm   253 GIFHAFYRILADEGVKALFKGAICRMMVMAPLFGIAQTVYYVGSAEKILGLEKGSRV 309

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GC2	NP_731657.2	PTZ00169	14..289	CDD:240302	135/281 (48%)
		Mito_carr	16..106	CDD:278578	53/95 (56%)
		Mito_carr	123..203	CDD:278578	33/79 (42%)
		Mito_carr	228..302	CDD:278578	38/73 (52%)
slc-25A18.2	NP_501198.1	Mito_carr	17..114	CDD:278578	55/100 (55%)
		PTZ00168	18..277	CDD:185494	132/275 (48%)
		Mito_carr	117..200	CDD:278578	39/94 (41%)
		Mito_carr	216..292	CDD:278578	39/76 (51%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	128	1.000	Domainoid score	I3298
eggNOG	1	0.900	-	-		E1_KOG0750
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53612
OrthoDB	1	1.010	-	-		D458796at33208
OrthoFinder	1	1.000	-	-		FOG0002230
OrthoInspector	1	1.000	-	-		mtm4728
orthoMCL	1	0.900	-	-		OOG6_104895
Panther	1	1.100	-	-	O	PTHR45678
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X982
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	12	11.790