Protein Alignment GC1 and SLC25A14

DIOPT Version :10

• Sequence 1: NP_650134.1
• Gene: GC1 / 41448
• FlyBaseID: FBgn0260743
• Length: 321
• Species: Drosophila melanogaster
• Sequence 2: NP_001269126.1
• Gene: SLC25A14 / 9016
• HGNCID: 10984
• Length: 353
• Species: Homo sapiens
• Alignment Length: 330
• Identity: 84/330 - (25%)
• Similarity: 128/330 - (38%)
• Gaps: 63/330 - (19%)

  Fly     2 SSSATIATPLPQPQHQQFALLPK-IINGGIAGIIGVTCVFPLDLVKTRL--QNQQIGPN-GERMY 62
            :::|.|........|:...|..| .:.||:|.|:.....||:||.||||  |.|.|... .|..|
Human    17 ATAAVIHQKSTTVSHEMSGLNWKPFVYGGLASIVAEFGTFPVDLTKTRLQVQGQSIDARFKEIKY 81

  Fly    63 NSMFDCFRKTYKAEGYFGMYRGSGVNILLITPEKAIKLTANDYFRHKLTTKDGKLPLTSQMVAGG 127
            ..||....:..|.||...:|.|....:|.......||:......:.....:.....|...|:.|.
Human    82 RGMFHALFRICKEEGVLALYSGIAPALLRQASYGTIKIGIYQSLKRLFVERLEDETLLINMICGV 146

  Fly   128 LAGAFQIIVTTPMELLKIQMQDAGRVAAAAKLAGKTVEKVSATQLASQLIKDKGIFGLYKGIGAT 192
            ::|.....:..|.::|||:||..|.:...: :.|..::          :.:.:|..||::.:.:
Human   147 VSGVISSTIANPTDVLKIRMQAQGSLFQGS-MIGSFID----------IYQQEGTRGLWRCLCS- 199

  Fly   193 GLRDVTFSIIYFPLFATLNDLGPRRNDGSGEAV-------------------------------- 225
              :.||..:::  |...:..|......||.|.|
Human   200 --KAVTGCVLW--LMPVIPALWEANAGGSLEGVVPTAQRAAIVVGVELPVYDITKKHLILSGMMG 260

  Fly   226 ------FWCSFLAGLAAGSTAALAVNPFDVVKTRLQAIKKADGEKE-FKGISDCITKTLKHEGPT 283
                  |..||..|||    .|||.||.|||:||:...:...|..: :||..|.|.|..||||..
Human   261 DTILTHFVSSFTCGLA----GALASNPVDVVRTRMMNQRAIVGHVDLYKGTVDGILKMWKHEGFF 321

  Fly   284 AFFKG 288
            |.:||
Human   322 ALYKG 326

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GC1	NP_650134.1	PTZ00169	37..294	CDD:240302	75/294 (26%)
SLC25A14	NP_001269126.1	Mito_carr	37..133	CDD:395101	28/95 (29%)
		Mito_carr	134..254	CDD:395101	23/135 (17%)
		Mito_carr	262..351	CDD:395101	29/69 (42%)