Protein Alignment GC1 and SLC25A33

DIOPT Version :10

• Sequence 1: NP_650134.1
• Gene: GC1 / 41448
• FlyBaseID: FBgn0260743
• Length: 321
• Species: Drosophila melanogaster
• Sequence 2: NP_115691.1
• Gene: SLC25A33 / 84275
• HGNCID: 29681
• Length: 321
• Species: Homo sapiens
• Alignment Length: 328
• Identity: 78/328 - (23%)
• Similarity: 142/328 - (43%)
• Gaps: 55/328 - (16%)

  Fly    15 QHQQFALLPKIINGGIAGIIGVTCVFPLDLVKTRLQNQQIG------P-------NGERMYN--- 63
            |.::..|| .:..||..|.:|.....||:::|||||:.::.      |       :|..|..
Human     6 QQKENTLL-HLFAGGCGGTVGAIFTCPLEVIKTRLQSSRLALRTVYYPQVHLGTISGAGMVRPTS 69

  Fly    64 ---SMFDCFRKTYKAEGYFGMYRGSGVNILLITPEKAIKLTANDYFRHKLTTKD---GKLPLTSQ 122
               .:|...:...:.||...::||.|.|::.:.|.:|:      ||......|:   |.....|.
Human    70 VTPGLFQVLKSILEKEGPKSLFRGLGPNLVGVAPSRAV------YFACYSKAKEQFNGIFVPNSN 128

  Fly   123 MVAGGLAGAFQIIVTT---PMELLKIQMQDAGRVAAAAKLAGKTVEKVSATQLASQLIKDKGIFG 184
            :|....||:...|..:   |:.::|.:||...:|..:        ::::..|.|..:.:.:||.|
Human   129 IVHIFSAGSAAFITNSLMNPIWMVKTRMQLEQKVRGS--------KQMNTLQCARYVYQTEGIRG 185

  Fly   185 LYKGIGATGLRDVTFSIIYFPLFATLNDL---GPRRNDGSGEAVFWCSFL-----AGLAAGSTAA 241
            .|:|:.|: ...::.:||.|.::.:|...   .|..:..:|......||.     |.|:.|..:.
Human   186 FYRGLTAS-YAGISETIICFAIYESLKKYLKEAPLASSANGTEKNSTSFFGLMAAAALSKGCASC 249

  Fly   242 LAVNPFDVVKTRLQAIKKADGEKEFKGISDCITKTLKHEGPTAFFKGGLCRMIVIAPLFGIAQTV 306
            :|. |.:|::|||    :.:|.| :|..........:.||..||::|...::|...|...|..:.
Human   250 IAY-PHEVIRTRL----REEGTK-YKSFVQTARLVFREEGYLAFYRGLFAQLIRQIPNTAIVLST 308

  Fly   307 YYL 309
            |.|
Human   309 YEL 311

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GC1	NP_650134.1	PTZ00169	37..294	CDD:240302	66/289 (23%)
SLC25A33	NP_115691.1	Mito_carr	7..123	CDD:395101	29/122 (24%)
		Solcar 1	9..118		28/115 (24%)
		Mito_carr	125..216	CDD:395101	22/99 (22%)
		Solcar 2	126..213		22/95 (23%)
		Solcar 3	231..315		24/87 (28%)
		Mito_carr	232..312	CDD:395101	24/86 (28%)