Protein Alignment GC1 and UCP3

DIOPT Version :10

• Sequence 1: NP_650134.1
• Gene: GC1 / 41448
• FlyBaseID: FBgn0260743
• Length: 321
• Species: Drosophila melanogaster
• Sequence 2: NP_003347.1
• Gene: UCP3 / 7352
• HGNCID: 12519
• Length: 312
• Species: Homo sapiens
• Alignment Length: 282
• Identity: 75/282 - (26%)
• Similarity: 118/282 - (41%)
• Gaps: 39/282 - (13%)

  Fly    24 KIINGGIAGIIGVTCVFPLDLVKTRLQ----NQQIGPNGERMYNSMFDCFRKTYKAEGYFGMYRG 84
            |.:..|.|........||||..|.|||    ||.:.......|..:........:.||....|.|
Human    16 KFLGAGTAACFADLVTFPLDTAKVRLQIQGENQAVQTARLVQYRGVLGTILTMVRTEGPCSPYNG 80

  Fly    85 SGVNILLITPEKAIKLTANDYFRHKLTTKDG-KLPLTSQMVAGGLAGAFQIIVTTPMELLKIQMQ 148
            ....:.......:|::...|..:...|.|.. ...||::::||...||..:....|.:::|::.|
Human    81 LVAGLQRQMSFASIRIGLYDSVKQVYTPKGADNSSLTTRILAGCTTGAMAVTCAQPTDVVKVRFQ 145

  Fly   149 DAGRVAAAAKLA-GKTVEKVSATQLASQLI-KDKGIFGLYKGIGATGLRD--------VTFSIIY 203
                  |:..|. .::..|.|.|..|.:.| :::|:.||:||.....:|:        ||:.|:.
Human   146 ------ASIHLGPSRSDRKYSGTMDAYRTIAREEGVRGLWKGTLPNIMRNAIVNCAEVVTYDILK 204

  Fly   204 FPL--FATLNDLGPRRNDGSGEAVFWCSFLAGLAAGSTAALAVNPFDVVKTRLQAIKKADGEKEF 266
            ..|  :..|.|..|            |.|::...||..|.:..:|.||||||.  :....|  ::
Human   205 EKLLDYHLLTDNFP------------CHFVSAFGAGFCATVVASPVDVVKTRY--MNSPPG--QY 253

  Fly   267 KGISDCITKTLKHEGPTAFFKG 288
            ....||:.|.:..||||||:||
Human   254 FSPLDCMIKMVAQEGPTAFYKG 275

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GC1	NP_650134.1	PTZ00169	37..294	CDD:240302	72/269 (27%)
UCP3	NP_003347.1	Mito_carr	10..110	CDD:395101	21/93 (23%)
		Solcar 1	11..105		20/88 (23%)
		Mito_carr	112..210	CDD:395101	26/103 (25%)
		Solcar 2	114..206		25/97 (26%)
		Mito_carr	214..303	CDD:395101	26/78 (33%)
		Solcar 3	215..300		26/77 (34%)
		Purine nucleotide binding. /evidence=ECO:0000250	279..301