Protein Alignment GC1 and UCP1

DIOPT Version :10

• Sequence 1: NP_650134.1
• Gene: GC1 / 41448
• FlyBaseID: FBgn0260743
• Length: 321
• Species: Drosophila melanogaster
• Sequence 2: NP_068605.1
• Gene: UCP1 / 7350
• HGNCID: 12517
• Length: 307
• Species: Homo sapiens
• Alignment Length: 268
• Identity: 72/268 - (26%)
• Similarity: 120/268 - (44%)
• Gaps: 16/268 - (5%)

  Fly    24 KIINGGIAGIIGVTCVFPLDLVKTRLQNQQIGPNGERM-YNSMFDCFRKTYKAEGYFGMYRGSGV 87
            ::.:.|||..:.....||||..|.|||.|...|....: |..:........|.||...:|.|...
Human    16 QLFSAGIAACLADVITFPLDTAKVRLQVQGECPTSSVIRYKGVLGTITAVVKTEGRMKLYSGLPA 80

  Fly    88 NILLITPEKAIKLTANDYFRHKLTT-KDGKLPLTSQMVAGGLAGAFQIIVTTPMELLKIQMQDAG 151
            .:.......::::...|..:..||. |:....|.|:::||...|...:.:..|.|::|:::|
Human    81 GLQRQISSASLRIGLYDTVQEFLTAGKETAPSLGSKILAGLTTGGVAVFIGQPTEVVKVRLQ--- 142

  Fly   152 RVAAAAKLAGKTVEKVSATQLASQLI-KDKGIFGLYKGIGATGLRDVTFSIIYFPLFATLNDLGP 215
               |.:.|.| ...:.:.|..|.::| ..:|:.||:||.....:|.|..:......:..:.:...
Human   143 ---AQSHLHG-IKPRYTGTYNAYRIIATTEGLTGLWKGTTPNLMRSVIINCTELVTYDLMKEAFV 203

  Fly   216 RRNDGSGEAVFWCSFLAGLAAGSTAALAVNPFDVVKTRLQAIKKADGEKEFKGISDCITKTLKHE 280
            :.|..:.:..  |..::.|.||..|....:|.||||||.  |....|  ::|.:.:|..|...:|
Human   204 KNNILADDVP--CHLVSALIAGFCATAMSSPVDVVKTRF--INSPPG--QYKSVPNCAMKVFTNE 262

  Fly   281 GPTAFFKG 288
            ||||||||
Human   263 GPTAFFKG 270

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GC1	NP_650134.1	PTZ00169	37..294	CDD:240302	69/255 (27%)
UCP1	NP_068605.1	Mito_carr	10..104	CDD:395101	20/87 (23%)
		Solcar 1	11..102		20/85 (24%)
		Mito_carr	111..206	CDD:395101	22/101 (22%)
		Solcar 2	111..201		22/96 (23%)
		Solcar 3	210..295		26/67 (39%)
		Mito_carr	215..300	CDD:395101	25/60 (42%)