Protein Alignment GC1 and SLC25A36

DIOPT Version :10

• Sequence 1: NP_650134.1
• Gene: GC1 / 41448
• FlyBaseID: FBgn0260743
• Length: 321
• Species: Drosophila melanogaster
• Sequence 2: XP_047304396.1
• Gene: SLC25A36 / 55186
• HGNCID: 25554
• Length: 343
• Species: Homo sapiens
• Alignment Length: 311
• Identity: 79/311 - (25%)
• Similarity: 135/311 - (43%)
• Gaps: 47/311 - (15%)

  Fly    28 GGIAGIIGVTCVFPLDLVKTRLQ-------------NQQIGPNGERMYN-SMFDCFRKTYKAEGY 78
            ||..|.| :||  ||::||||||             |...|.:..|:.: ....|.:...:.||.
Human    48 GGTVGAI-LTC--PLEVVKTRLQSSSVTLYISEVQLNTMAGASVNRVVSPGPLHCLKVILEKEGP 109

  Fly    79 FGMYRGSGVNILLITPEKAIKLTANDYFRHKLTTKDGKLPLTSQ--MVAGGLAGAFQIIVTTPME 141
            ..::||.|.|::.:.|.:||...|....:.||  .|...|.::|  |::..:||...|..|.|:.
Human   110 RSLFRGLGPNLVGVAPSRAIYFAAYSNCKEKL--NDVFDPDSTQVHMISAAMAGFTAITATNPIW 172

  Fly   142 LLKIQMQ-DAGRVAAAAKLAGKTVEKVSATQLASQLIKDKGIFGLYKGIGATGLRDVTFSIIYFP 205
            |:|.::| ||.........|.:.|.||..|.         |:.|.|:|:.|: ...::.::|:|.
Human   173 LIKTRLQLDARNRGERRMGAFECVRKVYQTD---------GLKGFYRGMSAS-YAGISETVIHFV 227

  Fly   206 LFATLND-------LGPRRNDGSG--EAVFWCSFLAGLAAGSTAALAV-NPFDVVKTRLQAIKKA 260
            ::.::..       .....||...  ||..:...:...|...|.|..: .|.:||:|||    :.
Human   228 IYESIKQKLLEYKTASTMENDEESVKEASDFVGMMLAAATSKTCATTIAYPHEVVRTRL----RE 288

  Fly   261 DGEKEFKGISDCITKTLKHEGPTAFFKGGLCRMIVIAPLFGIAQTVYYLGV 311
            :|.| ::.....::..::.||..:.::|....::...|...|....|.|.|
Human   289 EGTK-YRSFFQTLSLLVQEEGYGSLYRGLTTHLVRQIPNTAIMMATYELVV 338

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GC1	NP_650134.1	PTZ00169	37..294	CDD:240302	70/283 (25%)
SLC25A36	XP_047304396.1	Mito_carr	40..145	CDD:395101	31/101 (31%)
		Mito_carr	146..240	CDD:395101	25/103 (24%)
		Mito_carr	258..343	CDD:395101	19/86 (22%)