Protein Alignment GC1 and SLC25A37

DIOPT Version :10

• Sequence 1: NP_650134.1
• Gene: GC1 / 41448
• FlyBaseID: FBgn0260743
• Length: 321
• Species: Drosophila melanogaster
• Sequence 2: NP_057696.2
• Gene: SLC25A37 / 51312
• HGNCID: 29786
• Length: 338
• Species: Homo sapiens
• Alignment Length: 323
• Identity: 78/323 - (24%)
• Similarity: 138/323 - (42%)
• Gaps: 57/323 - (17%)

  Fly     1 MSSSATIATPLPQPQHQQFALLPKIINGGIAGIIGVTCVFPLDLVKTRLQNQQIGPNGERMYNSM 65
            :.:||:::|.:..              |.:|||:..:.::|:|.||||:|:  :.|:.:..|.|:
Human    39 LPTSASVSTHMTA--------------GAMAGILEHSVMYPVDSVKTRMQS--LSPDPKAQYTSI 87

  Fly    66 FDCFRKTYKAEGYFGMYRGSGVNILLITPEKA--------IKLTANDYFRHKLTTKDGKLPLTSQ 122
            :...:|..:.||::...||..|.|:...|..|        :|.|.||.|.|:     |...|.:.
Human    88 YGALKKIMRTEGFWRPLRGVNVMIMGAGPAHAMYFACYENMKRTLNDVFHHQ-----GNSHLANG 147

  Fly   123 MVAGGLAGAFQIIVTTPMELLK--IQMQDAGRVAAAAKLAGKTVEKVSATQLASQLIKDKGIFGL 185
             :||.:|......|..|.|::|  :||.::              :..||......:.:.:|:...
Human   148 -IAGSMATLLHDAVMNPAEVVKQRLQMYNS--------------QHRSAISCIRTVWRTEGLGAF 197

  Fly   186 YKGIGATGLRDVTFSIIYFPLFATLND-LGPRRNDGSGEAVFWCSFLAGLAAGSTAALAVNPFDV 249
            |:........::.|..|:|..:..|.: :.|.|.......:     ::|..||:.||.|..|.||
Human   198 YRSYTTQLTMNIPFQSIHFITYEFLQEQVNPHRTYNPQSHI-----ISGGLAGALAAAATTPLDV 257

  Fly   250 VKTRLQ-----AIKKADGEKEFKGISDCITKTLKHEGPTAFFKGGLCRMIVIAPLFGIAQTVY 307
            .||.|.     |:..|:......|:::......:..|...:|||...|:|...|...|:.:||
Human   258 CKTLLNTQENVALSLANISGRLSGMANAFRTVYQLNGLAGYFKGIQARVIYQMPSTAISWSVY 320

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GC1	NP_650134.1	PTZ00169	37..294	CDD:240302	66/272 (24%)
SLC25A37	NP_057696.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..42		0/2 (0%)
		Solcar 1	43..131		26/103 (25%)
		Mito_carr	44..136	CDD:395101	28/107 (26%)
		Solcar 2	141..225		18/98 (18%)
		Mito_carr	142..224	CDD:395101	18/96 (19%)
		Solcar 3	232..326		25/94 (27%)
		Mito_carr	<252..330	CDD:395101	19/69 (28%)