DRSC/TRiP Functional Genomics Resources

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Protein Alignment GC1 and Slc25a13

DIOPT Version :9

Sequence 1:NP_001262490.1 Gene:GC1 / 41448 FlyBaseID:FBgn0260743 Length:321 Species:Drosophila melanogaster
Sequence 2:NP_056644.1 Gene:Slc25a13 / 50799 MGIID:1354721 Length:676 Species:Mus musculus


Alignment Length:289 Identity:124/289 - (42%)
Similarity:173/289 - (59%) Gaps:28/289 - (9%)


- Green bases have known domain annotations that are detailed below.


  Fly    28 GGIAGIIGVTCVFPLDLVKTRLQNQQIGPN--GERMYNSMFDCFRKTYKAEGYFGMYRGSGVNIL 90
            |.|||.:|.|.|:|:||||||:|||:...:  ||.||.:.||||:|..:.||:||:|||....:|
Mouse   336 GSIAGAVGATAVYPIDLVKTRMQNQRSTGSFVGELMYKNSFDCFKKVLRYEGFFGLYRGLLPQLL 400

  Fly    91 LITPEKAIKLTANDYFRHKLTTKDGKLPLTSQMVAGGLAGAFQIIVTTPMELLKIQMQDAGRVAA 155
            .:.||||||||.||:.|.|...|||.:||.:::.|||.||..|:|.|.|:|::||::|.||.:..
Mouse   401 GVAPEKAIKLTVNDFVRDKFMHKDGSVPLLAEIFAGGCAGGSQVIFTNPLEIVKIRLQVAGEITT 465

  Fly   156 AAKLAGKTVEKVSATQLASQLIKDKGIFGLYKGIGATGLRDVTFSIIYFPLFATL-----NDLGP 215
            ..:::            |..:::|.|.||:|||..|..|||:.||.||||.:|.:     |:.| 
Mouse   466 GPRVS------------ALSVVRDLGFFGIYKGAKACFLRDIPFSAIYFPCYAHVKASFANEDG- 517

  Fly   216 RRNDGSGEAVFWCSFLAGLAAGSTAALAVNPFDVVKTRLQAIKKADGEKEFKGISDCITKTLKHE 280
            :.:.||       ..|||..||..||..|.|.||:|||||...:| |:..:.|::||..|.|:.|
Mouse   518 QVSPGS-------LLLAGAIAGMPAASLVTPADVIKTRLQVAARA-GQTTYNGVTDCFRKILREE 574

  Fly   281 GPTAFFKGGLCRMIVIAPLFGIAQTVYYL 309
            ||.|.:||...|:...:|.||:....|.|
Mouse   575 GPKALWKGVAARVFRSSPQFGVTLLTYEL 603

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
GC1NP_001262490.1 Mito_carr 36..113 CDD:278578 41/78 (53%)
Mito_carr 115..213 CDD:278578 38/102 (37%)
Mito_carr 226..307 CDD:278578 33/80 (41%)
Slc25a13NP_056644.1 N-terminal domain. /evidence=ECO:0000250|UniProtKB:Q9UJS0 2..295
EF-hand_7 17..81 CDD:290234
EFh 19..81 CDD:298682
Linker loop domain. /evidence=ECO:0000250|UniProtKB:O75746 296..311
Carrier domain. /evidence=ECO:0000250|UniProtKB:Q9UJS0 322..613 124/289 (43%)
PTZ00168 328..586 CDD:185494 118/270 (44%)
Mito_carr 330..423 CDD:278578 46/86 (53%)
Mito_carr 425..512 CDD:278578 37/98 (38%)
Mito_carr 517..609 CDD:278578 38/96 (40%)
C-terminal domain. /evidence=ECO:0000250|UniProtKB:Q9UJS0 614..676
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 1 1.030 - avgDist Average_Evolutionary_Distance R4126
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
32.940

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