DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GC1 and slc25a55b

DIOPT Version :9

Sequence 1:	NP_001262490.1	Gene:	GC1 / 41448	FlyBaseID:	FBgn0260743	Length:	321	Species:	Drosophila melanogaster
Sequence 2:	NP_001003448.1	Gene:	slc25a55b / 445054	ZFINID:	ZDB-GENE-040801-184	Length:	331	Species:	Danio rerio

Alignment Length:	324	Identity:	172/324 - (53%)
Similarity:	225/324 - (69%)	Gaps:	28/324 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 QQFALLPKIINGGIAGIIGVTCVFPLDLVKTRLQNQQIGPNGERMYNSMFDCFRKTYKAEGYFGM 81
            |..:|..|:||||:||::|||||||:||.|||||||:   ..:|:|.:|.||..||.::||||||
Zfish     4 QPISLPAKLINGGVAGLVGVTCVFPIDLAKTRLQNQR---GSQRVYKNMMDCLIKTVRSEGYFGM 65

  Fly    82 YRGSGVNILLITPEKAIKLTANDYFRHKLTTKDGKLPLTSQMVAGGLAGAFQIIVTTPMELLKIQ 146
            |||:.||:.|:||||||||.|||:||.:|:..|.||.:..:|:||..||..|:|||||||:||||
Zfish    66 YRGAAVNLTLVTPEKAIKLAANDFFRQRLSRGDLKLSVFQEMLAGCGAGMCQVIVTTPMEMLKIQ 130

  Fly   147 MQDAGRVAA---------AAKLAG--------------KTVEKVSATQLASQLIKDKGIFGLYKG 188
            :|||||:.|         ..||..              .::.||||.|:|.:|.:.|||.|||||
Zfish   131 LQDAGRLVAQQRNVPILHTVKLGAASPVLNYSYSVGPVSSIRKVSAVQIAQELFRTKGIQGLYKG 195

  Fly   189 IGATGLRDVTFSIIYFPLFATLNDLGPRRNDGSGEAVFWCSFLAGLAAGSTAALAVNPFDVVKTR 253
            :|||.:||:.||::||||||.:|.||....|  .:..|:.||::|..||.|||:||:|.||||||
Zfish   196 LGATLMRDIPFSVVYFPLFAHINQLGKTSED--SDVPFYWSFISGCVAGCTAAVAVSPCDVVKTR 258

  Fly   254 LQAIKKADGEKEFKGISDCITKTLKHEGPTAFFKGGLCRMIVIAPLFGIAQTVYYLGVAEGLLG 317
            ||::.|:..|..:.|:.|||.|.::.|||:||.||..||.:||||||||||.||::||.|.|||
Zfish   259 LQSLNKSANEDTYNGVVDCIRKIMRKEGPSAFLKGAGCRALVIAPLFGIAQVVYFIGVGEFLLG 322

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GC1	NP_001262490.1	Mito_carr	36..113	CDD:278578	48/76 (63%)
		Mito_carr	115..213	CDD:278578	56/120 (47%)
		Mito_carr	226..307	CDD:278578	46/80 (58%)
slc25a55b	NP_001003448.1	Mito_carr	4..96	CDD:278578	58/94 (62%)
		Mito_carr	100..214	CDD:278578	52/113 (46%)
		Mito_carr	227..312	CDD:278578	46/84 (55%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	135	1.000	Domainoid score	I4914
eggNOG	1	0.900	-	-		E1_KOG0750
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	351	1.000	Inparanoid score	I2237
OMA	1	1.010	-	-		QHG53612
OrthoDB	1	1.010	-	-		D458796at33208
OrthoFinder	1	1.000	-	-		FOG0002230
OrthoInspector	1	1.000	-	-		mtm6363
orthoMCL	1	0.900	-	-		OOG6_104895
Panther	1	1.100	-	-	O	PTHR45678
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X982
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	13	12.840