DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GC1 and mfrn

DIOPT Version :9

Sequence 1:	NP_001262490.1	Gene:	GC1 / 41448	FlyBaseID:	FBgn0260743	Length:	321	Species:	Drosophila melanogaster
Sequence 2:	NP_651600.1	Gene:	mfrn / 43353	FlyBaseID:	FBgn0039561	Length:	379	Species:	Drosophila melanogaster

Alignment Length:	287	Identity:	69/287 - (24%)
Similarity:	112/287 - (39%)	Gaps:	66/287 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    25 IINGGIAGIIGVTCVFPLDLVKTRLQNQQIGPNGERMYNSMF----DCFRKTYKAEGYFGMYRGS 85
            :|:|.:|.:|......|.|::|.|:|          ||||.:    .|.|..||.||:...||..
  Fly   111 VISGAVATLIHDAISSPTDVIKQRMQ----------MYNSPYTSVVSCVRDIYKREGFKAFYRAY 165

  Fly    86 GVNILLITPEKAIKLTANDYFRHKLTTKDGKLPLTSQMVAGGLAGAFQIIVTTPMELLK--IQMQ 148
            |..:::..|.:.|..|..::|::|:.. :.|......|.||..|||....||||::::|  :..|
  Fly   166 GTQLVMNLPYQTIHFTTYEFFQNKMNL-ERKYNPPVHMAAGAAAGACAAAVTTPLDVIKTLLNTQ 229

  Fly   149 DAGRVAAAAKLAGKTVEKVSATQLASQLIKDKGIFGLYKGIGATGLRDVTFSIIYFPLFATLNDL 213
            :.|......:.:.|.....             |..|.::|         |.:.:.:.:.||
  Fly   230 ETGLTRGMIEASRKIYHMA-------------GPLGFFRG---------TTARVLYSMPAT---- 268

  Fly   214 GPRRNDGSGEAVFWCS------FLAGLAAGS-----TAALAVNPFDVVKTRLQAIKKADGEKEFK 267
                      |:.|.:      :|.||.|..     |.:......|.|..|....::.|.|:|..
  Fly   269 ----------AICWSTYEFFKFYLCGLDADQYKSSITGSSEPRKADYVLPRTTDEEQIDQEREAA 323

  Fly   268 GISDCITKTLKHEGPTAFFKGGLCRMI 294
            ...| .|.|| |..||:....|..:.:
  Fly   324 KEKD-TTATL-HSAPTSVNASGAIKTV 348

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GC1	NP_001262490.1	Mito_carr	36..113	CDD:278578	23/80 (29%)
		Mito_carr	115..213	CDD:278578	21/99 (21%)
		Mito_carr	226..307	CDD:278578	20/80 (25%)
mfrn	NP_651600.1	Mito_carr	13..98	CDD:278578
		PTZ00168	17..280	CDD:185494	50/215 (23%)
		Mito_carr	107..190	CDD:278578	26/88 (30%)
		Mito_carr	<215..282	CDD:278578	16/102 (16%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45441244
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930