DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GC1 and SCaMC

DIOPT Version :9

Sequence 1:	NP_001262490.1	Gene:	GC1 / 41448	FlyBaseID:	FBgn0260743	Length:	321	Species:	Drosophila melanogaster
Sequence 2:	NP_729802.1	Gene:	SCaMC / 39415	FlyBaseID:	FBgn0052103	Length:	583	Species:	Drosophila melanogaster

Alignment Length:	319	Identity:	88/319 - (27%)
Similarity:	140/319 - (43%)	Gaps:	55/319 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    25 IINGGIAGIIGVTCVFPLDLVKTRLQNQQIGPNGERMYNSMFDCFRKTYKAEGYFGMYRGSGVNI 89
            ::.|||||.:..||..|||.:|..||.|.     :||  .:.:|........|...|:||:|:|:
  Fly   289 LVAGGIAGAVSRTCTAPLDRIKVYLQVQT-----QRM--GISECMHIMLNEGGSRSMWRGNGINV 346

  Fly    90 LLITPEKAIKLTANDYFRHKLTTKDG--KLPLTSQMVAGGLAGAFQIIVTTPMELLK--IQMQDA 150
            |.|.||.|.|..|.:..:..:...||  ::.:..:..||..||.....:..|||:||  :.::..
  Fly   347 LKIAPETAFKFAAYEQMKRLIRGDDGSRQMSIVERFYAGAAAGGISQTIIYPMEVLKTRLALRRT 411

  Fly   151 GRVAAAAKLAGKTVEKVSATQLASQLIKDKGIFGLYKGIGATGLRDVTFSIIYFPLFATLNDLGP 215
            |:.|..|..|.|             :.|.:|:...|:|.....|..:.::.|...::.||.....
  Fly   412 GQYAGIADAAVK-------------IYKQEGVRSFYRGYVPNILGILPYAGIDLAVYETLKRRYI 463

  Fly   216 RRNDGSGEAVFWCSFLAGLAAGSTAA----LAVNPFDVVKTRLQA----------------IKKA 260
            ..:|.:.:.    |||..||.|||::    |...|..:|:|||||                :|.:
  Fly   464 ANHDNNEQP----SFLVLLACGSTSSTLGQLCSYPLALVRTRLQAQAAETIANQKRKTQIPLKSS 524

  Fly   261 D---GEKEFKGISDCITKTLKHEGPTAFFKGGLCRMIVIAPLFGIAQTVY-YLGVAEGL 315
            |   ||:...|:   ..|.::.||.|..::|.....:.:.|...|:..|| |...|.|:
  Fly   525 DAHSGEETMTGL---FRKIVRQEGLTGLYRGITPNFLKVLPAVSISYVVYEYTSRALGI 580

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GC1	NP_001262490.1	Mito_carr	36..113	CDD:278578	25/76 (33%)
		Mito_carr	115..213	CDD:278578	23/101 (23%)
		Mito_carr	226..307	CDD:278578	28/103 (27%)
SCaMC	NP_729802.1	FRQ1	100..247	CDD:227455
		EFh	116..176	CDD:238008
		EFh	186..242	CDD:238008
		Mito_carr	285..370	CDD:278578	30/87 (34%)
		Mito_carr	375..463	CDD:278578	22/100 (22%)
		Mito_carr	470..581	CDD:278578	33/118 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45442092
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840