DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GC1 and PMP34

DIOPT Version :9

Sequence 1:	NP_001262490.1	Gene:	GC1 / 41448	FlyBaseID:	FBgn0260743	Length:	321	Species:	Drosophila melanogaster
Sequence 2:	NP_001246615.1	Gene:	PMP34 / 38532	FlyBaseID:	FBgn0052250	Length:	314	Species:	Drosophila melanogaster

Alignment Length:	193	Identity:	45/193 - (23%)
Similarity:	98/193 - (50%)	Gaps:	7/193 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 QFALLPKIINGGIAGIIGVTCVFPLDLVKTRLQNQQIGPNGERM---YNSMFDCFRKTYKAEGYF 79
            |.:.|..::.|.|||||.|....|..:|.|||:.:.:....:.:   |.::.:..:...:.||..
  Fly   106 QHSALKDLLLGSIAGIINVLTTTPFWVVNTRLRMRNVAGTSDEVNKHYKNLLEGLKYVAEKEGIA 170

  Fly    80 GMYRGSGVNILLITPEKAIKLTANDYF-RHKLTTKDGKLPLTSQMVAGGLAGAFQIIVTTPMELL 143
            |::.|:..:::|:: ..|::....:.. |:.:....|::...|....|.:|.||..::|.|::|:
  Fly   171 GLWSGTIPSLMLVS-NPALQFMMYEMLKRNIMRFTGGEMGSLSFFFIGAIAKAFATVLTYPLQLV 234

  Fly   144 KIQMQDAGRVAAA--AKLAGKTVEKVSATQLASQLIKDKGIFGLYKGIGATGLRDVTFSIIYF 204
            :.:.:...:.:.:  :..||.|....|..:|...:::.:||.||::|:.|..|:.|..:.:.|
  Fly   235 QTKQRHRSKESDSKPSTSAGSTPRTESTLELMISILQHQGIRGLFRGLEAKILQTVLTAALMF 297

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GC1	NP_001262490.1	Mito_carr	36..113	CDD:278578	14/80 (18%)
		Mito_carr	115..213	CDD:278578	23/92 (25%)
		Mito_carr	226..307	CDD:278578
PMP34	NP_001246615.1	Mito_carr	15..96	CDD:278578
		Mito_carr	105..202	CDD:278578	22/96 (23%)
		Mito_carr	214..303	CDD:278578	21/84 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45442015
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840