Protein Alignment GC1 and slc25a12

DIOPT Version :10

• Sequence 1: NP_650134.1
• Gene: GC1 / 41448
• FlyBaseID: FBgn0260743
• Length: 321
• Species: Drosophila melanogaster
• Sequence 2: NP_997947.1
• Gene: slc25a12 / 337675
• ZFINID: ZDB-GENE-031006-11
• Length: 682
• Species: Danio rerio
• Alignment Length: 288
• Identity: 123/288 - (42%)
• Similarity: 167/288 - (57%)
• Gaps: 26/288 - (9%)

  Fly    28 GGIAGIIGVTCVFPLDLVKTRLQNQQIGPN--GERMYNSMFDCFRKTYKAEGYFGMYRGSGVNIL 90
            |.|||..|.|.|:|:||||||:|||:...:  ||.||.:.|||.:|..:.||:||.|||....::
Zfish   335 GSIAGATGATAVYPIDLVKTRMQNQRSTGSFVGELMYKNSFDCAKKVLRYEGFFGFYRGLLPQLI 399

  Fly    91 LITPEKAIKLTANDYFRHKLTTKDGKLPLTSQMVAGGLAGAFQIIVTTPMELLKIQMQDAGRVAA 155
            .:.||||||||.||:.|.|.||.|..:||.::::|||.||..|:|.|.|:|::||::|.||.:..
Zfish   400 GVAPEKAIKLTVNDFVRDKFTTNDDTIPLAAEILAGGCAGGSQVIFTNPLEIVKIRLQVAGEITT 464

  Fly   156 AAKLAGKTVEKVSATQLASQLIKDKGIFGLYKGIGATGLRDVTFSIIYFPLF----ATLNDLGPR 216
            ..:::            |..:|:|.|.||||||..|..|||:.||.||||::    |.|.|
Zfish   465 GPRVS------------ALSVIRDLGFFGLYKGTKACFLRDIPFSAIYFPVYAHTKALLAD---- 513

  Fly   217 RNDGSGEAVFWCSFLAGLAAGSTAALAVNPFDVVKTRLQAIKKADGEKEFKGISDCITKTLKHEG 281
             .||...|:...|  ||..||..||..|.|.||:|||||...:| |:..:.|:.||..|.:|.||
Zfish   514 -EDGRLGALQLLS--AGAIAGVPAASLVTPADVIKTRLQVAARA-GQTTYNGVIDCFRKIMKEEG 574

  Fly   282 PTAFFKGGLCRMIVIAPLFGIAQTVYYL 309
            ..|.:||...|:...:|.|.:....|.|
Zfish   575 FRALWKGAGARVFRSSPQFAVTLLTYEL 602

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GC1	NP_650134.1	PTZ00169	37..294	CDD:240302	114/262 (44%)
slc25a12	NP_997947.1	EF-hand_7	14..81	CDD:463900
		EFh_PEF	19..190	CDD:355382
		EF-hand motif	19..49	CDD:320054
		EF-hand motif	57..94	CDD:320054
		EF-hand motif	95..126	CDD:320054
		EF-hand motif	133..161	CDD:320054
		EF-hand motif	163..190	CDD:320054
		Mito_carr	329..422	CDD:395101	45/86 (52%)
		Mito_carr	424..511	CDD:395101	38/98 (39%)
		Mito_carr	516..608	CDD:395101	35/90 (39%)