Protein Alignment GC1 and SLC25A47

DIOPT Version :10

• Sequence 1: NP_650134.1
• Gene: GC1 / 41448
• FlyBaseID: FBgn0260743
• Length: 321
• Species: Drosophila melanogaster
• Sequence 2: NP_997000.2
• Gene: SLC25A47 / 283600
• HGNCID: 20115
• Length: 308
• Species: Homo sapiens
• Alignment Length: 323
• Identity: 89/323 - (27%)
• Similarity: 142/323 - (43%)
• Gaps: 51/323 - (15%)

  Fly    26 INGGIAGIIGVTCVFPLDLVKTRLQNQQIGPNGERMYNSMFDCFRKTYKAEGYFGMYRGSGVNIL 90
            :.|.|.|:.||...:|||.||.|:|.       |..|..::.|.|.||..|..:|.|||..:.:.
Human     4 VAGAIGGVCGVAVGYPLDTVKVRIQT-------EPKYTGIWHCVRDTYHRERVWGFYRGLSLPVC 61

  Fly    91 LITPEKAIKLTANDYFRHKLT--------TKDGKLPLTSQMVAGGLAGAFQIIVTTPMELLKIQM 147
            .::...::....   :||.|.        ..|.|.......::|..:|..::.:|:|.|:.|:::
Human    62 TVSLVSSVSFGT---YRHCLAHICRLRYGNPDAKPTKADITLSGCASGLVRVFLTSPTEVAKVRL 123

  Fly   148 Q-------DAGRVAAAAKLAGKTVEKV----------SATQLASQLIKDKGIFGLYKGIGATGLR 195
            |       ...|::|:..||...:..|          ......:.:.:::|:.|||||..|..||
Human   124 QTQTQAQKQQRRLSASGPLAVPPMCPVPPACPEPKYRGPLHCLATVAREEGLCGLYKGSSALVLR 188

  Fly   196 D----VTFSIIYFPLFATLNDLGPRRNDGSGEAVFWCSFLAGLAAGSTAALAVNPFDVVKTRLQA 256
            |    .|:.:.|..|...|:..|..|.|..|..|      ||..||..|.....|.||:|:||||
Human   189 DGHSFATYFLSYAVLCEWLSPAGHSRPDVPGVLV------AGGCAGVLAWAVATPMDVIKSRLQA 247

  Fly   257 IKKADGEKEFKGISDCITKTLKHEGPTAFFKG---GLCRMIVIAPLFGIAQTVYYLGVAEGLL 316
              ...|::.::|:..|:..:::.|||...|||   ..||...:..:..:|... .|.:|.|||
Human   248 --DGQGQRRYRGLLHCMVTSVREEGPRVLFKGLVLNCCRAFPVNMVVFVAYEA-VLRLARGLL 307

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GC1	NP_650134.1	PTZ00169	37..294	CDD:240302	78/288 (27%)
SLC25A47	NP_997000.2	Solcar 1	1..80		26/85 (31%)
		Mito_carr	2..77	CDD:395101	24/82 (29%)
		Solcar 2	93..206		25/112 (22%)
		Mito_carr	100..208	CDD:395101	25/107 (23%)
		Solcar 3	215..302		29/95 (31%)
		Mito_carr	221..302	CDD:395101	27/89 (30%)