DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GC1 and K02F3.2

DIOPT Version :9

Sequence 1:	NP_001262490.1	Gene:	GC1 / 41448	FlyBaseID:	FBgn0260743	Length:	321	Species:	Drosophila melanogaster
Sequence 2:	NP_001263698.1	Gene:	K02F3.2 / 175242	WormBaseID:	WBGene00019326	Length:	716	Species:	Caenorhabditis elegans

Alignment Length:	301	Identity:	125/301 - (41%)
Similarity:	172/301 - (57%)	Gaps:	31/301 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 KIINGGIAGIIGVTCVFPLDLVKTRLQNQQIGPN--GERMYNSMFDCFRKTYKAEGYFGMYRGSG 86
            :.:.|.:||..|.|.|:|:||||||:|||:...:  ||.||.:..|||:|..|.||..|:|||..
Worm   381 RFLLGSVAGACGATAVYPIDLVKTRMQNQRTSGSFVGEVMYKNSLDCFKKVVKFEGLLGLYRGLL 445

  Fly    87 VNILLITPEKAIKLTANDYFRHKLTTKDGKLPLTSQMVAGGLAGAFQIIVTTPMELLKIQMQDAG 151
            ..|:.:.||||||||.|||.|.|. |||||:||..:::|||..|..|::.|.|:|::||::|.||
Worm   446 PQIVGVAPEKAIKLTMNDYMRDKF-TKDGKIPLYGEIIAGGTGGMCQVVFTNPLEIVKIRLQTAG 509

  Fly   152 RVAAAAKLAGKTVEKVSATQLASQLIKDKGIFGLYKGIGATGLRDVTFSIIYFPLFATLNDLGPR 216
            .|..|.|..|           ...::|:.|..|||||..|..|||:.||.||||.:|... |...
Worm   510 EVQQAGKKIG-----------VFTVLKELGFLGLYKGSRACFLRDIPFSAIYFPAYAHAK-LASA 562

  Fly   217 RNDG--SGEAVFWCSFLAGL-AAGSTAALAVNPFDVVKTRLQAIKKADGEKEFKGISDCITKTLK 278
            ..||  |...:|..:|:||: |||     .|.|.||:|||||...:| |:..:.|:.||..|.:|
Worm   563 DEDGMNSPGTLFASAFIAGVPAAG-----LVTPADVIKTRLQVAARA-GQTTYNGVIDCARKLIK 621

  Fly   279 HEGPTAFFKGGLCRMIVIAPLFGIA-------QTVYYLGVA 312
            .|||.:.:||...|:...:|.|.:.       |.::|:..|
Worm   622 EEGPMSLWKGTAARVCRSSPQFAVTLLTYEVLQRLFYVDFA 662

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GC1	NP_001262490.1	Mito_carr	36..113	CDD:278578	41/78 (53%)
		Mito_carr	115..213	CDD:278578	39/97 (40%)
		Mito_carr	226..307	CDD:278578	32/88 (36%)
K02F3.2	NP_001263698.1	EF-hand_8	71..121	CDD:290545
		PTZ00184	135..>237	CDD:185504
		EFh	206..>227	CDD:298682
		Mito_carr	376..473	CDD:278578	47/92 (51%)
		PTZ00169	382..656	CDD:240302	123/292 (42%)
		Mito_carr	473..558	CDD:278578	39/95 (41%)
		Mito_carr	569..658	CDD:278578	33/94 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4126
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.940